Background Malaria is a leading cause of morbidity and mortality, with approximately 225
million clinical episodes and> 1.2 million deaths annually attributed to malaria. Development …

Over 80% of all malaria deaths occur in children under 5 years of age. Malaria control
strategies have been progressively shifted to specific populations and/or areas to maximize …

Background The world's first malaria vaccine RTS, S provides only partial protection against
Plasmodium falciparum infections. The explanation for such low efficacy is unclear. This …

Malaria remains an important cause of morbidity and mortality among children in sub-
Saharan Africa despite recent reductions in malaria incidence in some parts of Africa …

P. ovale and P. knowlesi [1] and two of these species, P. falciparum and P. vivax, are
responsible for most cases of human mortality and morbidity [2]. The World Health …

The process of Plasmodium merozoites invasion is a complex multi-step process. In
understanding the mechanisms leading to successful merozoites invasion, a group of …

Erythrocyte invasion by Plasmodium falciparum merozoites is an essential step for parasite
survival and proliferation. Invasion is mediated by multiple ligands, which could be …

abstract 29 Vaccines are one of the most effective interventions to improve public health,
however, the generation of 30 highly effective vaccines for many diseases has remained …