The formation of new blood vessels, called angiogenesis, is an essential pathophysiological
process in which several families of regulators have been implicated. Among these, vascular …

The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

The prevalence of peripheral arterial disease (PAD) in the United States exceeds 10 million
people, and PAD is a significant cause of morbidity and mortality across the globe. PAD is …

The vasculature plays an indispensible role in organ development and maintenance of
tissue homeostasis, such that disturbances to it impact greatly on developmental and …

Although the currently available pharmacological assays can cure most pathological
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …

Angiogenesis is touted as a fundamental procedure in the regeneration and restoration of
different tissues. The induction of de novo blood vessels seems to be vital to yield a …

Abstract Aims Hutchinson-Gilford progeria syndrome (HGPS) is an accelerated ageing
syndrome associated with premature vascular disease and death due to heart attack and …

Vascular tissue engineering has significant potential to make a major impact on a wide array
of clinical problems. Continued progress in understanding basic vascular biology will be …

Stem cell transplantation has been recognized as a promising strategy to induce the
regeneration of injured and diseased tissues and sustain therapeutic molecules for …

Cardiovascular disease is the leading cause of death worldwide and is often associated with
partial or full occlusion of the blood vessel network in the affected organs. Restoring blood …