Attenuating the effects of novel COVID-19 (SARS-CoV-2) infection-induced cytokine storm and the implications

AB Rowaiye, OA Okpalefe… - Journal of …, 2021 - Taylor & Francis
The COVID-19 pandemic constitutes an arduous global health challenge, and the
increasing number of fatalities calls for the speedy pursuit of a remedy. This review …

Challenges and opportunities for antiviral monoclonal antibodies as COVID-19 therapy

C Cruz-Teran, K Tiruthani, M McSweeney, A Ma… - Advanced drug delivery …, 2021 - Elsevier
To address the COVID-19 pandemic, there has been an unprecedented global effort to
advance potent neutralizing mAbs against SARS-CoV-2 as therapeutics. However, historical …

SARS-CoV-2: emerging role in the pathogenesis of various thyroid diseases

AK Murugan, AS Alzahrani - Journal of Inflammation Research, 2021 - Taylor & Francis
Abstract Coronavirus disease-2019 (COVID-19) is asymptomatic in most cases, but it is
impartible and fatal in fragile and elderly people. Heretofore, more than four million people …

Role of SARS-CoV-2 spike-protein-induced activation of microglia and mast cells in the pathogenesis of neuro-COVID

TC Theoharides, D Kempuraj - Cells, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). About 45% of COVID-19 patients experience several symptoms a …

COVID-19 and outcomes in patients with inflammatory bowel disease: systematic review and meta-analysis

K Tripathi, G Godoy Brewer… - Inflammatory bowel …, 2022 - academic.oup.com
Background Our understanding of coronavirus disease 2019 (COVID-19) and its
implications for patients with inflammatory bowel diseases (IBD) is rapidly evolving. We …

The dynamic association between COVID-19 and chronic disorders: An updated insight into prevalence, mechanisms and therapeutic modalities

SK Alyammahi, SM Abdin, DW Alhamad… - Infection, Genetics and …, 2021 - Elsevier
The devastating pandemic of coronavirus disease 2019 (COVID-19) has caused thousands
of deaths and left millions of restless patients suffering from its complications. Increasing …

Overview of COVID-19 inflammatory pathogenesis from the therapeutic perspective

C Lee, WJ Choi - Archives of pharmacal research, 2021 - Springer
The novel beta coronavirus (SARS-CoV-2, designated as COVID-19) that is responsible for
severe acute respiratory syndrome has devastated the global economy and health care …

Rapid electrochemical dual-target biosensor composed of an Aptamer/MXene hybrid on Au microgap electrodes for cytokines detection

S Noh, H Lee, J Kim, H Jang, J An, C Park… - Biosensors and …, 2022 - Elsevier
Rapid detection methods for cytokine storm markers, such as tumor necrosis factor α (TNF-α)
and interferon gamma (IFN-γ), are required. Herein, we describe the fabrication of a rapid …

[HTML][HTML] Prothrombotic changes in patients with COVID‐19 are associated with disease severity and mortality

FA von Meijenfeldt, S Havervall, J Adelmeijer… - Research and practice …, 2021 - Elsevier
Abstract Background and Aims Patients with severe coronavirus disease 2019 (COVID‐19)
are at significant risk of thrombotic complications. However, their prothrombotic state is …

Innate immune cell activation causes lung fibrosis in a humanized model of long COVID

L Cui, Z Fang, CM De Souza, T Lerbs… - Proceedings of the …, 2023 - National Acad Sciences
COVID-19 remains a global pandemic of an unprecedented magnitude with millions of
people now developing “COVID lung fibrosis.” Single-cell transcriptomics of lungs of patients …