Network meta-analysis of antibiotic resistance patterns in gram-negative bacterial infections: a comparative study of carbapenems, fluoroquinolones, and …

G Muteeb - Frontiers in microbiology, 2023 - frontiersin.org
Introduction Antimicrobial resistance poses a grave global threat, particularly with the
emergence of multidrug-resistant gram-negative bacterial infections, which severely limit …

A Shortcut from Genome to Drug: The Employment of Bioinformatic Tools to Find New Targets for Gastric Cancer Treatment

DMS Brito, OG Lima, FP Mesquita, EL da Silva… - Pharmaceutics, 2023 - mdpi.com
Gastric cancer (GC) is a highly heterogeneous, complex disease and the fifth most common
cancer worldwide (about 1 million cases and 784,000 deaths worldwide in 2018). GC has a …

Potential drug targets for tumors identified through Mendelian randomization analysis

N Song, P Shi, K Cui, L Zeng, Z Wang, W Di, J Li… - Scientific Reports, 2024 - nature.com
According to the latest cancer research data, there are a significant number of new cancer
cases and a substantial mortality rate each year. Although a substantial number of clinical …

Occurrence and characterization of β-lactamase-producing bacteria in biomedical wastewater and in silico enhancement of antibiotic efficacy

SJ Mannan, S Akash, SA Jahin, AT Saqif… - Frontiers in …, 2024 - frontiersin.org
Wastewater discharged from hospitals is a recognized contributor to the dissemination of
antibiotic-resistant bacteria and their associated genetic traits into the environment. This …

A practical electrochemical method for determining the inhibitory activity of New Delhi Metallo-β-lactamase-1 inhibitors

H Gan, Y Liang, Y Tang, M Huang, Y Wan - Microchemical Journal, 2023 - Elsevier
A practical electrochemical method for the determination of the inhibitory activity of New
Delhi metallo-β-lactamase-1 (NDM-1) inhibitors was established with a bare pencil graphite …

Rational design of novel compounds to serve as potential NDM-1 inhibitors using molecular docking, molecular dynamics simulation, and physicochemical studies

T Salih, PG Ali - Molecular Simulation, 2023 - Taylor & Francis
ABSTRACT New Delhi Metallo-β-lactamase (NDM-1) is an enzyme that hydrolyses a wide
range of β-lactam antibiotics, including most carbapenems, leading to antimicrobial …

Ghazala Muteeb

MT Mascellino, M Eryilmaz, Z Islam - 2023 - europepmc.org
Methods We searched PubMed, Web of Sciences, Scopus, Scholarly, Medline, Embase, and
Cochrane databases up to August 27, 2023. Studies showing antibiotic resistance in clinical …

[PDF][PDF] Design and Discovery of Silmitasertib-based Drugs as a Potential Casein Kinase II Inhibitor for Cholangiocarcinoma through Hybrid In-silico Ligand-Based …

P Tajane, N Kayande, A Bhosale, S Deore, H Tare - academia.edu
This research investigates the design and discovery of silmitasertib-based drugs as potential
inhibitors of casein kinase II (CK2) for cholangiocarcinoma using hybrid in-silico methods …

[PDF][PDF] Nature's Treasure Trove: Exploring the β-Carotene Bounty in Moringa oleifera Leaves through In Silico Analysis and Quantitative Gene Expression

S Kayode, S Paris - 1924 - researchgate.net
Moringa oleifera, commonly known as the drumstick tree, has long been celebrated for its
nutritional prowess and medicinal properties. Among its myriad bioactive compounds, β …

[PDF][PDF] Moringa Marvel: Unraveling the Bioactive Potency of β-Carotene in Moringa oleifera Leaves via In Silico Exploration and Gene Expression Insights

S Kayode, S Paris - 1924 - researchgate.net
In the realm of nutritional science, Moringa oleifera has emerged as a botanical marvel,
renowned for its multifaceted health benefits. This study delves into the bioactive potential of …