Wet granulation is a key step in the pharmaceutical manufacturing of solid-dosage forms.
Wet granulation is used in pharmaceutical production to enhance formulation qualities such …

Wet granulation is a very important unit operation that finds applications in many industries
mainly pharmaceutical and chemical industries. Various granulation technologies in batch …

This multiauthor review article aims to bring readers up to date with some of the current
trends in the field of process analytical technology (PAT) by summarizing each aspect of the …

Population balance models are tools for the study of dispersed systems, such as granular
materials, polymers, colloids and aerosols. They are applied with increasing frequency …

High shear wet granulation (HSWG) is considered a complicated and multivariate
pharmaceutical process that is influenced by a large number of variables derived from …

Current trends in pharmaceutical wet granulation have been shifted from traditional
approach to systematic and modern approaches, enabling the production of highly …

In this study, a novel mechanistic model for a wet granulation process is presented,
combining the techniques of population balance modeling and discrete element methods to …

A hybrid model was developed for simulation of continuous wet granulation of
pharmaceutical formulations via twin-screw granulator. The model was based on population …

In this study, a compartmental population balance model (CPBM) is developed as a
predictive tool of particle size distribution (PSD) for wet granulation in co-rotating twin-screw …

High-shear wet granulation is a complex process that, in turn, makes scale-up a challenging
task. Scale-up of high-shear wet granulation process has been studied extensively in the …