Molecular targeted therapy plays an increasingly important role in the treatment of metastatic
pheochromocytomas and paragangliomas (PPGLs), which are rare tumors but remain …

Simple Summary Pheochromocytomas and abdominal paragangliomas (PPGLs) are rare.
They can be discovered incidentally by imaging with computed tomography or magnetic …

Pheochromocytomas (PC) and paragangliomas (PG) are rare neuroendocrine tumors
associated with autonomic nerves. Here we use single-nuclei RNA-seq and bulk-tissue …

The mechanisms triggering metastasis in pheochromocytoma/paraganglioma are unknown,
hindering therapeutic options for patients with metastatic tumors (mPPGL). Herein we show …

This article aims to review current concepts in diagnosing and managing
pheochromocytoma and paraganglioma (PPGL). Personalized genetic testing is vital, as 40 …

Abstract Context Pheochromocytomas and paragangliomas (PPGLs) with pathogenic
mutations in the succinate dehydrogenase subunit B (SDHB) are associated with a high …

Background No randomised controlled trial has ever been done in patients with metastatic
phaeochromocytomas and paragangliomas. Preclinical and first clinical evidence suggested …

Pheochromocytomas/paragangliomas (PPGL) are rare, metastatic, and potentially fatal
neuroendocrine tumors, often neglected because they present symptoms similar to other …

Pheochromocytomas and paragangliomas are the most heritable endocrine tumors. In
addition to the inherited mutation other driver mutations have also been identified in tumor …

Aggressive pheochromocytomas and paragangliomas (PPGLs) are difficult to treat, and
molecular targeting is being increasingly considered, but with variable results. This study …