[HTML][HTML] The interaction between ferroptosis and inflammatory signaling pathways

Y Chen, ZM Fang, X Yi, X Wei, DS Jiang - Cell death & disease, 2023 - nature.com
Ferroptosis is an iron-dependent regulated cell death driven by excessive lipid peroxidation.
Inflammation is one common and effective physiological event that protects against various …

[HTML][HTML] Spotlight on pyroptosis: role in pathogenesis and therapeutic potential of ocular diseases

M Chen, R Rong, X Xia - Journal of neuroinflammation, 2022 - Springer
Pyroptosis is a programmed cell death characterized by swift plasma membrane disruption
and subsequent release of cellular contents and pro-inflammatory mediators (cytokines) …

[HTML][HTML] Cadmium induces liver dysfunction and ferroptosis through the endoplasmic stress-ferritinophagy axis

Z He, P Shen, L Feng, H Hao, Y He, G Fan, Z Liu… - Ecotoxicology and …, 2022 - Elsevier
Cadmium (Cd) is a type of high-risk heavy metal that can damage organs such as the liver,
but its mechanism is not yet clear. Ferroptosis is a newly discovered mode of regulatory cell …

[HTML][HTML] Ferroptosis and its role in chronic diseases

W Hu, K Liang, H Zhu, C Zhao, H Hu, S Yin - Cells, 2022 - mdpi.com
Ferroptosis, which has been widely associated with many diseases, is an iron-dependent
regulated cell death characterized by intracellular lipid peroxide accumulation. It exhibits …

[HTML][HTML] Disulfiram: mechanisms, applications, and challenges

J Lanz, N Biniaz-Harris, M Kuvaldina, S Jain, K Lewis… - Antibiotics, 2023 - mdpi.com
Background: Since disulfiram's discovery in the 1940s and its FDA approval for alcohol use
disorder, other indications have been investigated. This review describes potential clinical …

Asiatic acid alleviates LPS-induced acute kidney injury in broilers by inhibiting oxidative stress and ferroptosis via activation of the Nrf2 pathway

W Qiu, X Zhang, X Pang, J Huang, S Zhou… - Food and Chemical …, 2022 - Elsevier
Asiatic acid (AA), a triterpenoid compound isolated from Centella asiatica, has anti-
inflammatory, antioxidant and anticancer biological characteristics. To explore the effect of …

Galangin attenuates myocardial ischemic reperfusion-induced ferroptosis by targeting Nrf2/Gpx4 signaling pathway

T Yang, H Liu, C Yang, H Mo, X Wang… - Drug Design …, 2023 - Taylor & Francis
Purpose Myocardial ischemic reperfusion injury (MIRI) is a crucial clinical problem globally.
The molecular mechanisms of MIRI need to be fully explored to develop new therapeutic …

Icariside II induces ferroptosis in renal cell carcinoma cells by regulating the miR-324-3p/GPX4 axis

R Yu, Y Zhou, S Shi, X Wang, S Huang, Y Ren - Phytomedicine, 2022 - Elsevier
Abstract Icariside II (ICS II) is an active flavonoid having anti-tumor properties. However, the
role of ICS II in renal cell carcinoma (RCC) and its underlying mechanisms have not been …

[HTML][HTML] Ferroptosis, pyroptosis and necroptosis in acute respiratory distress syndrome

Y Zheng, Y Huang, Y Xu, L Sang, X Liu, Y Li - Cell Death Discovery, 2023 - nature.com
Acute respiratory distress syndrome (ARDS) is an acute and uncontrolled pulmonary
inflammation caused by various insults. Cell death is a critical mechanism in the …

[HTML][HTML] Ferroptosis: A potential target for the intervention of intervertebral disc degeneration

LP Zhou, RJ Zhang, CY Jia, L Kang… - Frontiers in …, 2022 - frontiersin.org
Ferroptosis, an iron-dependent form of programmed cell death marked by phospholipid
peroxidation, is regulated by complex cellular metabolic pathways including lipid …