Hepatic microcirculatory disturbance in liver diseases: intervention with traditional Chinese medicine
P Liu, WL Liang, RT Huang, XX Chen… - Frontiers in …, 2024 - frontiersin.org
The liver, a complex parenchymal organ, possesses a distinctive microcirculatory system
crucial for its physiological functions. An intricate interplay exists between hepatic …
crucial for its physiological functions. An intricate interplay exists between hepatic …
The 3Rs in experimental liver disease
S Martinez-Lopez, E Angel-Gomis, E Sanchez-Ardid… - Animals, 2023 - mdpi.com
Simple Summary This article provides a review of recent studies that explore the application
of the 3Rs in experimental animal models of liver disease, comparing different models for a …
of the 3Rs in experimental animal models of liver disease, comparing different models for a …
A rule-based multiscale model of hepatic stellate cell plasticity: Critical role of the inactivation loop in fibrosis progression
M Bouguéon, V Legagneux, O Hazard… - PLOS Computational …, 2024 - journals.plos.org
Hepatic stellate cells (HSC) are the source of extracellular matrix (ECM) whose
overproduction leads to fibrosis, a condition that impairs liver functions in chronic liver …
overproduction leads to fibrosis, a condition that impairs liver functions in chronic liver …
Modélisation en langage Kappa de la dynamique des cellules étoilées hépatiques durant le développement et la réversion de la fibrose
M Bouguéon - 2023 - inria.hal.science
La fibrose hépatique est une réponse de cicatrisation excessive induite par des lésions
chroniques. Elle se caractérise par une accumulation de matrice extracellulaire (MEC) …
chroniques. Elle se caractérise par une accumulation de matrice extracellulaire (MEC) …
베이지안모델기반약물유사화합물의간독성예측
채한화， 박원철， 진영배， 임다정 - 한국산학기술학회논문지, 2024 - dbpia.co.kr
간 독성을 예측하는 것은 약물유사-화합물의 안전성 평가에 중요하다. 간 독성은 약물유사-
화합물의 물리화학적 성질, 특히 구조적 특성과 관련이 있다. 이번 연구에서 정량적 구조-독성 …
화합물의 물리화학적 성질, 특히 구조적 특성과 관련이 있다. 이번 연구에서 정량적 구조-독성 …