Objectives: Review the risk factors for coronary artery disease. Outline screening
recommendations for coronary artery disease. Identify diet and exercise recommendations …

Cardiovascular diseases caused by atherosclerosis do not typically manifest before middle
age; however, the disease process begins early in life. Preclinical atherosclerosis can be …

Abstract Background and Objective As the most common cardiovascular defect, coronary
artery disease (CAD), also called ischemic heart disease, is one of the substantial causes of …

Importance Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in
the United States, accounting for 1 of every 3 deaths among adults. Objective To update the …

What happens when patients suddenly stop their medications? We study the health
consequences of drug interruptions caused by large, abrupt, and arbitrary changes in price …

Cardiovascular disease remains the top cause of morbidity and mortality in the United
States. Atherosclerotic plaques are known to start in adolescence, and, therefore, young …

Lipid Management to Prevent CVD Management of serum cholesterol level is a central
objective in preventing cardiovascular events. Current guidelines recommend calculation of …

Objectives Heterozygous familial hypercholesterolaemia (FH) confers a significant risk for
premature cardiovascular disease (CVD). However, the estimated prevalence of FH varies …

Background Polygenic risk scores (PRSs) can stratify populations into cardiovascular
disease (CVD) risk groups. We aimed to quantify the potential advantage of adding …

Importance Down syndrome is the most common chromosomal condition, and average life
expectancy has increased substantially, from 25 years in 1983 to 60 years in 2020. Despite …