A review of malaria vaccine clinical projects based on the WHO rainbow table
L Schwartz, GV Brown, B Genton, VS Moorthy - Malaria journal, 2012 - Springer
Abstract Development and Phase 3 testing of the most advanced malaria vaccine, RTS,
S/AS01, indicates that malaria vaccine R&D is moving into a new phase. Field trials of …
S/AS01, indicates that malaria vaccine R&D is moving into a new phase. Field trials of …
Integrated approach to malaria control
C Shiff - Clinical microbiology reviews, 2002 - Am Soc Microbiol
Malaria draws global attention in a cyclic manner, with interest and associated financing
waxing and waning according to political and humanitarian concerns. Currently we are on …
waxing and waning according to political and humanitarian concerns. Currently we are on …
Efficacy of the RTS, S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial
Background Development of an effective malaria vaccine could greatly contribute to disease
control. RTS, S/AS02A is a pre-erythrocytic vaccine candidate based on Plasmodium …
control. RTS, S/AS02A is a pre-erythrocytic vaccine candidate based on Plasmodium …
Efficacy of RTS, S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial
KA Bojang, PJM Milligan, M Pinder, L Vigneron… - The Lancet, 2001 - thelancet.com
Summary Background RTS, S/AS02 is a pre-erythrocytic malaria vaccine based on the
circumsporozoite surface protein of Plasmodium falciparum fused to HBsAg, incorporating a …
circumsporozoite surface protein of Plasmodium falciparum fused to HBsAg, incorporating a …
Intermittent treatment for malaria and anaemia control at time of routine vaccinations in Tanzanian infants: a randomised, placebo-controlled trial
D Schellenberg, C Menendez, E Kahigwa, J Aponte… - The Lancet, 2001 - thelancet.com
Background Clinical malaria and severe anaemia are major causes of paediatric hospital
admission and death in many malaria-endemic settings. In the absence of an effective and …
admission and death in many malaria-endemic settings. In the absence of an effective and …
Malaria vaccine developments
Large gains in the reduction of malaria mortality in the early 20th century were lost in
subsequent decades. Malaria now kills 2–3 million people yearly. Implementation of malaria …
subsequent decades. Malaria now kills 2–3 million people yearly. Implementation of malaria …
An estimation of the entomological inoculation rate for Ifakara: a semi‐urban area in a region of intense malaria transmission in Tanzania
C Drakeley, D Schellenberg, J Kihonda… - Tropical Medicine & …, 2003 - Wiley Online Library
An entomological study on vectors of malaria and their relative contribution to Plasmodium
falciparum transmission in the semi‐urban area of Ifakara, south‐eastern Tanzania, was …
falciparum transmission in the semi‐urban area of Ifakara, south‐eastern Tanzania, was …
Safety and efficacy of novel malaria vaccine regimens of RTS, S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP
We assessed a combination multi-stage malaria vaccine schedule in which RTS, S/AS01B
was given concomitantly with viral vectors expressing multiple-epitope thrombospondin …
was given concomitantly with viral vectors expressing multiple-epitope thrombospondin …
Structural and immunological principles leading to chemically synthesized, multiantigenic, multistage, minimal subunit-based vaccine development
Dedicated to the memory of Professors Henry G. Kunkel and Bruce Merrifield (Rockefeller
University, New York), who introduced us to the fascinating worlds of immunology and …
University, New York), who introduced us to the fascinating worlds of immunology and …
Vaccines for preventing malaria (SPf66)
PM Graves, H Gelband… - Cochrane Database …, 1996 - cochranelibrary.com
Background A malaria vaccine is badly needed. SPf66 was one of the earliest vaccines
developed. It is a synthetic peptide vaccine containing antigens from the blood stages of …
developed. It is a synthetic peptide vaccine containing antigens from the blood stages of …