Ten Years of BrainAGE as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained?

K Franke, C Gaser - Frontiers in neurology, 2019 - frontiersin.org
With the aging population, prevalence of neurodegenerative diseases is increasing, thus
placing a growing burden on individuals and the whole society. However, individual rates of …

Imaging structural and functional brain development in early childhood

JH Gilmore, RC Knickmeyer, W Gao - Nature Reviews Neuroscience, 2018 - nature.com
In humans, the period from term birth to∼ 2 years of age is characterized by rapid and
dynamic brain development and plays an important role in cognitive development and risk of …

Image processing and analysis methods for the Adolescent Brain Cognitive Development Study

DJ Hagler Jr, SN Hatton, MD Cornejo, C Makowski… - Neuroimage, 2019 - Elsevier
Abstract The Adolescent Brain Cognitive Development (ABCD) Study is an ongoing,
nationwide study of the effects of environmental influences on behavioral and brain …

[HTML][HTML] Accurate brain age prediction with lightweight deep neural networks

H Peng, W Gong, CF Beckmann, A Vedaldi… - Medical image …, 2021 - Elsevier
Deep learning has huge potential for accurate disease prediction with neuroimaging data,
but the prediction performance is often limited by training-dataset size and computing …

Predicting age using neuroimaging: innovative brain ageing biomarkers

JH Cole, K Franke - Trends in neurosciences, 2017 - cell.com
The brain changes as we age and these changes are associated with functional
deterioration and neurodegenerative disease. It is vital that we better understand individual …

[HTML][HTML] Multimodality neuroimaging brain-age in UK biobank: relationship to biomedical, lifestyle, and cognitive factors

JH Cole - Neurobiology of aging, 2020 - Elsevier
The brain-age paradigm is proving increasingly useful for exploring aging-related disease
and can predict important future health outcomes. Most brain-age research uses structural …

MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14 468 individuals worldwide

VM Bashyam, G Erus, J Doshi, M Habes, IM Nasrallah… - Brain, 2020 - academic.oup.com
Deep learning has emerged as a powerful approach to constructing imaging signatures of
normal brain ageing as well as of various neuropathological processes associated with …

Development of the cerebral cortex across adolescence: a multisample study of inter-related longitudinal changes in cortical volume, surface area, and thickness

CK Tamnes, MM Herting, AL Goddings… - Journal of …, 2017 - Soc Neuroscience
Before we can assess and interpret how developmental changes in human brain structure
relate to cognition, affect, and motivation, and how these processes are perturbed in clinical …

Brain age and other bodily 'ages': implications for neuropsychiatry

JH Cole, RE Marioni, SE Harris, IJ Deary - Molecular psychiatry, 2019 - nature.com
As our brains age, we tend to experience cognitive decline and are at greater risk of
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …

Predicting brain-age from multimodal imaging data captures cognitive impairment

F Liem, G Varoquaux, J Kynast, F Beyer, SK Masouleh… - Neuroimage, 2017 - Elsevier
The disparity between the chronological age of an individual and their brain-age measured
based on biological information has the potential to offer clinically relevant biomarkers of …