Venous thromboembolism (VTE) is a significant contributor to morbidity and mortality. To
advance our understanding of the biology contributing to VTE, we conducted a genome …

Severe acute respiratory syndrome coronavirus 2 infection (COVID-19) is known to induce
severe inflammation and activation of the coagulation system, resulting in a prothrombotic …

Venous thromboembolism (VTE) represents a leading cause of global mortality, however,
the determinants that contribute to thrombus development remain incompletely understood …

Venous thromboembolism is a significant cause of mortality, yet its genetic determinants are
incompletely defined. We performed a discovery genome-wide association study in the …

Background A large proportion of pulmonary embolism (PE) heritability remains
unexplained, particularly among the East Asian (EAS) population. Our study aims to expand …

Background The protein C anticoagulant system plays a key role in maintaining the
hemostatic balance. Although several studies have identified thrombomodulin gene (THBD) …

Race and ethnicity are associated with risk of venous thromboembolism in population-based
studies. Blacks/African Americans have a higher incidence, whereas Asians/Pacific …

Venous thromboembolism (VTE) has a strong genetic component. This review summarizes
what is known at the seventeen genes that are now well established to harbour VTE …

Endothelial cells actively maintain an anti-thrombotic environment; loss of this protective
function may lead to thrombosis and systemic coagulopathy. The transcription factor ERG is …

Sickle cell disease (SCD) patients are at a four-to 100-fold increased risk for thrombosis
compared with the general population, although the mechanisms and risk factors are not …