Purpose: Anterior uveitis is the most common anatomic subset of uveitis. We developed a
novel multi-parametric flow cytometry panel to identify immune dysregulation signatures in …

Background Acute anterior uveitis (AAU) affects up to 40% of patients with axial
spondyloarthritis (axSpA). An effective treatment for patients with axSpA that reduces the risk …

Non-radiographic axial spondyloarthritis (nr-axSpA) is a complex disease process that is
part of the spectrum of axial spondyloarthritis (axSpA). This article reviews the current state …

Ankylosing spondylitis (AS) is a common chronic immune-mediated arthropathy affecting
primarily the spine and pelvis. The condition is strongly associated with HLA-B* 27 as well …

Several recent genome-wide association studies (GWAS) identified susceptibility loci/genes
for Behçet's disease (BD). However, no study has specifically investigated the genetic …

Purpose Evidence exists that the interleukin (IL)‐10 family of cytokines is involved in
autoimmune diseases. The aim of this study was to analyse the levels of the IL‐10 family …

Previous studies show that endoplasmic reticulum-associated aminopeptidase
(ERAP1/ERAP2) and runt-related transcription factor 3 (RUNX3) gene polymorphisms are …

Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that can lead to ankylosis
by secondary ossification of inflammatory lesions, with progressive disability and a …

The microbiome is strongly implicated in a broad spectrum of immune-mediated diseases.
Data support the concept that HLA molecules shape the microbiome. We provide …

Psoriatic arthritis (PsA) is a chronic inflammatory disease that presents with psoriasis (PsO),
peripheral and axial arthropathy. The heterogeneity of disease presentation leads to the …