[HTML][HTML] The multifaceted role of plasminogen in inflammation

B Heissig, Y Salama, S Takahashi, T Osada, K Hattori - Cellular signalling, 2020 - Elsevier
A fine-tuned activation and deactivation of proteases and their inhibitors are involved in the
execution of the inflammatory response. The zymogen/proenzyme plasminogen is converted …

[HTML][HTML] Cytokine storm syndrome in severe COVID-19

P Ruscitti, O Berardicurti, A Iagnocco… - Autoimmunity …, 2020 - ncbi.nlm.nih.gov
Dear Editor, we read with interest the article by McGonagle et al., which has been recently
published on this Journal [1]. This article highlights the role of pro-inflammatory cytokines in …

[HTML][HTML] Коронавирусная болезнь 2019 (COVID-19) и иммуновоспалительные ревматические заболевания: на перекрестке проблем тромбовоспаления и …

ЕЛ Насонов, ТВ Бекетова, ТМ Решетняк… - Научно …, 2020 - cyberleninka.ru
Воспаление и свертывание крови составляют основу защиты организма от
потенциально патогенных механических и биологических воздействий внешней и …

[HTML][HTML] Explanatory predictive model for COVID-19 severity risk employing machine learning, shapley addition, and LIME

M Laatifi, S Douzi, H Ezzine, CE Asry, A Naya… - Scientific Reports, 2023 - nature.com
The rapid spread of SARS-CoV-2 threatens global public health and impedes the operation
of healthcare systems. Several studies have been conducted to confirm SARS-CoV-2 …

Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor

A Gartung, J Yang, VP Sukhatme… - Proceedings of the …, 2019 - National Acad Sciences
Although chemotherapy is a conventional cancer treatment, it may induce a protumorigenic
microenvironment by triggering the release of proinflammatory mediators. In this study, we …

Highly conserved s2m element of SARS-CoV-2 dimerizes via a kissing complex and interacts with host miRNA-1307-3p

JA Imperatore, CL Cunningham… - Nucleic acids …, 2022 - academic.oup.com
The ongoing COVID-19 pandemic highlights the necessity for a more fundamental
understanding of the coronavirus life cycle. The causative agent of the disease, SARS-CoV …

[HTML][HTML] Clinical utility of inflammatory biomarkers in COVID-19 in direct comparison to other respiratory infections—A prospective cohort study

M Lampart, N Zellweger, S Bassetti, S Tschudin-Sutter… - PloS one, 2022 - journals.plos.org
Background Inflammatory biomarkers are associated with severity of coronavirus disease
2019 (COVID-19). However, direct comparisons of their utility in COVID-19 versus other …

[HTML][HTML] Macrophage activation syndrome and COVID-19

R Otsuka, K Seino - Inflammation and regeneration, 2020 - Springer
An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating
pandemic. As we have not developed curative medicine and effective vaccine, the end of …

JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation

LK Meyer, KC Verbist, S Albeituni… - Blood, The Journal …, 2020 - ashpublications.org
Cytokine storm syndromes (CSS) are severe hyperinflammatory conditions characterized by
excessive immune system activation leading to organ damage and death. Hemophagocytic …

[HTML][HTML] Nanotechnology as a shield against COVID-19: current advancement and limitations

M Rai, S Bonde, A Yadav, A Bhowmik, S Rathod… - Viruses, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a global health problem that the WHO declared a pandemic …