Cancer is still one of the major causes of death worldwide. Even if its comprehension is
improving continuously, the complexity and heterogeneity of this group of diseases …

Immunotherapy has become a fourth pillar in the treatment of brain tumors and, when
combined with radiation therapy, may improve patient outcomes and reduce the …

Background Mathematical modeling of biological processes is widely used to enhance
quantitative understanding of bio-medical phenomena. This quantitative knowledge can be …

Recently, mathematical modeling and simulation of diseases and their treatments have
enabled the prediction of clinical outcomes and the design of optimal therapies on a …

Mechanotherapy is a groundbreaking approach to impact carcinogenesis. Cells sense and
respond to mechanical stimuli, translating them into biochemical signals in a process known …

Radiotherapy is involved in 50% of all cancer treatments and 40% of cancer cures. Most of
these treatments are delivered in fractions of equal doses of radiation (Fractional Equivalent …

Recurrent high grade glioma patients face a poor prognosis for which no curative treatment
option currently exists. In contrast to prescribing high dose hypofractionated stereotactic …

Gliomas are the most frequent type of primary brain tumours. Low grade gliomas (LGGs,
WHO grade II gliomas) may grow very slowly for the long periods of time, however they …

Chemotherapy is a common treatment for advanced prostate cancer. The standard
approach relies on cytotoxic drugs, which aim at inhibiting proliferation and promoting cell …

Low-grade gliomas are primary brain tumors that arise from glial cells and are usually
treated with temozolomide (TMZ) as a chemotherapeutic option. They are often incurable …