Personalised antiplatelet therapies for coronary artery disease: what the future holds

D Capodanno, DJ Angiolillo - European Heart Journal, 2023 - academic.oup.com
Coronary artery disease (CAD) is one of the leading causes of death globally, and
antiplatelet therapy is crucial for both its prevention and treatment. Antiplatelet drugs such as …

Shorter Dual Antiplatelet Therapy for Older Adults After Percutaneous Coronary Intervention: A Systematic Review and Network Meta-Analysis

DY Park, JR Hu, Y Jamil, MD Kelsey… - JAMA Network …, 2024 - jamanetwork.com
Importance The optimal duration of dual antiplatelet therapy (DAPT) for older adults after
percutaneous coronary intervention (PCI) is uncertain because they are simultaneously at …

Sex-Based Outcomes of Dual-Antiplatelet Therapy After Percutaneous Coronary Intervention: A Pairwise and Network Meta-Analysis

TA Agbaedeng, JJ Noubiap, KA Roberts, DP Chew… - Drugs, 2024 - Springer
Background Although dual antiplatelet therapy (DAPT) improves the outcomes of patients
undergoing percutaneous coronary intervention (PCI), sex-specific differences in efficacy …

[HTML][HTML] Randomized evaluation of 5-month Ticagrelor monotherapy after 1-month dual-antiplatelet therapy in patients with acute coronary syndrome treated with drug …

C Gao, B Zhu, J Liu, Z Jiang, T Hu, Q Wang… - BMC Cardiovascular …, 2024 - Springer
Background Patients treated with drug-coated balloons (DCB) have the theoretical
advantage of adopting a low-intensity antiplatelet regimen due to the absence of struts and …

P2Y12 Inhibitor Monotherapy vs Dual Antiplatelet Therapy After Deployment of a Drug-Eluting Stent: The SHARE Randomized Clinical Trial

PK Min, TS Kang, YH Cho, SS Cheong… - JAMA network …, 2024 - jamanetwork.com
Importance P2Y12 inhibitor monotherapy after dual antiplatelet therapy (DAPT; a P2Y12
inhibitor plus aspirin) for a brief duration has recently emerged as an attractive alternative for …

[HTML][HTML] Advances in clinical cardiology 2021: a summary of key clinical trials

P Savage, B Cox, K Linden, J Coburn… - Advances in …, 2022 - Springer
Introduction Over the course of 2021, numerous key clinical trials with valuable contributions
to clinical cardiology were published or presented at major international conferences. This …

Aspirin-free strategy for percutaneous coronary intervention in acute coronary syndrome based on the subtypes of acute coronary syndrome and high bleeding risk …

Y Obayashi, M Natsuaki, H Watanabe… - European Heart …, 2024 - academic.oup.com
Background and aims High bleeding risk (HBR) and acute coronary syndrome (ACS)
subtypes are critical in determining bleeding and cardiovascular event risk after …

What is the optimal duration of antiplatelet therapy for patients with coronary heart disease?

B Otieno, C Ibecheozor, MS Williams - Current atherosclerosis reports, 2023 - Springer
Abstract Purpose of Review Optimal duration of antiplatelet therapy continues to attract
extensive debates and has been progressively adjusted in the setting of advancements in …

Antiplatelet De-Escalation Strategies in Patients Undergoing Percutaneous Coronary Intervention

A Spirito, SL Krishnan, D Capodanno… - Circulation …, 2024 - Am Heart Assoc
Dual antiplatelet therapy—the combination of aspirin and a P2Y12 inhibitor—remains the
standard antiplatelet regimen recommended to prevent ischemic complications immediately …

Biodegradable Polymer Versus Polymer-Free Ultrathin Sirolimus-Eluting Stents: Analysis of the Stent Arm Registry From the HOST-IDEA Randomized Trial

JK Han, S Yang, D Hwang, SH Park… - Circulation …, 2024 - Am Heart Assoc
BACKGROUND: The efficacy and safety of each third-generation drug-eluting stent with
ultrathin struts and advanced polymer technology remain unclear. We investigated the …