Obesity is now a worldwide epidemic ensuing an increase in comorbidities' prevalence,
such as insulin resistance, type 2 diabetes (T2D), metabolic dysfunction-associated fatty …

Obesity is a chronic disease associated with increased risk of obesity-related complications
and mortality. Our better understanding of the weight regulation mechanisms and the role of …

Introduction: Obesity affects nearly 1 in 4 European adults increasing their risk for mortality
and physical and psychological morbidity. Obesity is a chronic relapsing disease …

The complications associated with adult obesity are overwhelming national healthcare
systems. No country has yet implemented a successful population-level strategy to reverse …

Obesity is a condition associated with an increased risk of metabolic disorders, and in
particular of type-2 diabetes (T2D). The treatment and prevention of obesity and associated …

Background Recent studies suggest that tirzepatide, a dual glucose-dependent
insulinotropic-peptide (GIP) and glucagon-like peptide-1 receptor agonist (GLP-1 RA), has …

Abstract Background The triglyceride glucose (TyG) index, which is a new surrogate
indicator of insulin resistance (IR), is thought to be associated with many diseases, such as …

A sedentary lifestyle and an unhealthy diet increase the risk of obesity. People with obesity
experience adipocyte hypertrophy and hyperplasia, which increases the production of …

Metabolic diseases are becoming increasingly common in modern society. Therefore, it is
essential to develop effective drugs or new treatments for metabolic diseases. As an active …

Importance Obesity-related cancers account for 40% of all cancers in the US. Healthy food
consumption is a modifiable factor shown to reduce obesity-related cancer mortality, but …