Insights into COVID-19: Perspectives on Drug Remedies and Host Cell Responses

AM Awad, K Hansen, D Del Rio, D Flores… - Biomolecules, 2023 - mdpi.com
In light of the COVID-19 global pandemic caused by SARS-CoV-2, ongoing research has
centered on minimizing viral spread either by stopping viral entry or inhibiting viral …

Beyond an inflammatory mediator: Interleukin‐1 in neurophysiology

TS Lima - Experimental Physiology, 2023 - Wiley Online Library
Since its discovery in the early 1940s, the interleukin‐1 (IL‐1) cytokine family has been
associated primarily with acute and chronic inflammation. The family member IL‐1β is …

Autism spectrum disorder and a possible role of anti-inflammatory treatments: experience in the pediatric allergy/immunology clinic

H Jyonouchi - Frontiers in Psychiatry, 2024 - frontiersin.org
Autism spectrum disorder (ASD1) is a behaviorally defined syndrome encompassing a
markedly heterogeneous patient population. Many ASD subjects fail to respond to the 1st …

Evaluation of anakinra in the management of patients with COVID-19 infection: A randomized clinical trial

EZI Elmekaty, A Maklad, R Abouelhassan… - Frontiers in …, 2023 - frontiersin.org
Background The global COVID-19 pandemic led to substantial clinical and economic
outcomes with catastrophic consequences. While the majority of cases has mild to moderate …

Adverse drug reactions associated with COVID-19 management

V Chavda, P Dodiya, V Apostolopoulos - … -Schmiedeberg's Archives of …, 2024 - Springer
The emergence of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
outbreak, which causes COVID-19, had a devastating impact on both people's lives and the …

Clinically Evaluated COVID-19 Drugs with Therapeutic Potential for Biological Warfare Agents

ID Dechtman, R Ankory, K Sokolinsky, E Krasner… - Microorganisms, 2023 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak resulted in
hundreds of millions of coronavirus cases, as well as millions of deaths worldwide …

Lessons we learned during the past four challenging years in the COVID-19 era: pharmacotherapy, long COVID complications, and vaccine development

P Ghasemiyeh, S Mohammadi-Samani - Virology Journal, 2024 - Springer
About four years have passed since the detection of the first cases of COVID-19 in China.
During this lethal pandemic, millions of people have lost their lives around the world. Since …

Drug-drug interactions between COVID-19 therapeutics and psychotropic medications

A Cuomo, G Barillà, G Serafini, A Aguglia… - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction The coronavirus (COVID-19) pandemic has led to as well as
exacerbated mental health disorders, leading to increased use of psychotropic medications …

[HTML][HTML] Interplay of host and viral factors in inflammatory pathway mediated cytokine storm during RNA virus infection

R Chaudhary, A Meher, P Krishnamoorthy… - Current Research in …, 2023 - Elsevier
RNA viruses always have been a serious concern for human health by causing several
outbreaks, often pandemics. The excessive mortality and deaths associated with the …

Investigation of an aminothiazole-based scaffold as an anti-inflammatory agent: Potential application in the management of cytokine storm in SARS-CoV-19

MA Ganie, SM Ansari, R Choudhary, F Fayaz… - Journal of Molecular …, 2024 - Elsevier
Aminothiazole-based structures, including compounds like anakinra, nitazoxanide,
amiphenazole, and tizoxanide, along with cytokine-blocking agents such as tocilizumab and …