This comprehensive review delves into cancer's complexity, focusing on adhesion,
metastasis, and inhibition. It explores the pivotal role of these factors in disease progression …

Nanosized drug formulations are broadly explored for the improvement of cancer therapy.
Prediction of in vivo nanoparticle (NP) behavior, however, is challenging, given the …

Metastatic renal cell carcinoma (RCC) remains an incurable disease for most patients
highlighting an urgent need for new treatments. However, the preclinical investigation of …

ABSTRACT Ir (III) and Ru (II) polypyridyl complexes are promising photosensitizers (PSs) for
photodynamic therapy (PDT) due to their outstanding photophysical properties. Herein, one …

The environment created during embryogenesis contributes to reducing aberrations that
drive structural malformations and tumorigenesis. In this study, we investigate the anti …

Metabolic reprogramming is a significant hallmark of cancer that promotes chemoresistance
by allowing tumor tissues to adapt to changes in the tumor microenvironment caused by …

Melanoma is characterized by high metastatic potential favored by the epithelial-to-
mesenchymal transition (EMT), leading melanoma cells to exhibit a spectrum of typical EMT …

Abstract Background/Aims Liver cancer ranks third in cancer-related deaths globally,
projected to exceed one million annually by 2030. Existing therapies have significant …

Over the past decade, the development of three-dimensional (3D) models has increased
exponentially, facilitating the unravelling of fundamental and essential cellular mechanisms …

Cancer therapy is on the brink of a significant transformation with the inclusion of patient-
derived organoids (PDOs) in drug development. These three-dimensional cell cultures …