Epilepsy and brain network hubs

J Royer, BC Bernhardt, S Larivière, E Gleichgerrcht… - …, 2022 - Wiley Online Library
Epilepsy is a disorder of brain networks. A better understanding of structural and dynamic
network properties may improve epilepsy diagnosis, treatment, and prognostics. Hubs are …

Neuroimaging and connectomics of drug‐resistant epilepsy at multiple scales: From focal lesions to macroscale networks

S Tavakol, J Royer, AJ Lowe, L Bonilha, JI Tracy… - …, 2019 - Wiley Online Library
Epilepsy is among the most common chronic neurologic disorders, with 30%‐40% of
patients having seizures despite antiepileptic drug treatment. The advent of brain imaging …

[HTML][HTML] Geometric constraints on human brain function

JC Pang, KM Aquino, M Oldehinkel, PA Robinson… - Nature, 2023 - nature.com
The anatomy of the brain necessarily constrains its function, but precisely how remains
unclear. The classical and dominant paradigm in neuroscience is that neuronal dynamics …

Mapping neurotransmitter systems to the structural and functional organization of the human neocortex

JY Hansen, G Shafiei, RD Markello, K Smart… - Nature …, 2022 - nature.com
Neurotransmitter receptors support the propagation of signals in the human brain. How
receptor systems are situated within macro-scale neuroanatomy and how they shape …

Global waves synchronize the brain's functional systems with fluctuating arousal

RV Raut, AZ Snyder, A Mitra, D Yellin, N Fujii… - Science …, 2021 - science.org
We propose and empirically support a parsimonious account of intrinsic, brain-wide
spatiotemporal organization arising from traveling waves linked to arousal. We hypothesize …

Topographic organization of the human subcortex unveiled with functional connectivity gradients

Y Tian, DS Margulies, M Breakspear, A Zalesky - Nature neuroscience, 2020 - nature.com
Brain atlases are fundamental to understanding the topographic organization of the human
brain, yet many contemporary human atlases cover only the cerebral cortex, leaving the …

BrainSpace: a toolbox for the analysis of macroscale gradients in neuroimaging and connectomics datasets

R Vos de Wael, O Benkarim, C Paquola… - Communications …, 2020 - nature.com
Understanding how cognitive functions emerge from brain structure depends on quantifying
how discrete regions are integrated within the broader cortical landscape. Recent work …

Local molecular and global connectomic contributions to cross-disorder cortical abnormalities

JY Hansen, G Shafiei, JW Vogel, K Smart… - Nature …, 2022 - nature.com
Numerous brain disorders demonstrate structural brain abnormalities, which are thought to
arise from molecular perturbations or connectome miswiring. The unique and shared …

Microstructural and functional gradients are increasingly dissociated in transmodal cortices

C Paquola, R Vos De Wael, K Wagstyl… - PLoS …, 2019 - journals.plos.org
While the role of cortical microstructure in organising neural function is well established, it
remains unclear how structural constraints can give rise to more flexible elements of …

Gradients of structure–function tethering across neocortex

B Vázquez-Rodríguez, LE Suárez… - Proceedings of the …, 2019 - National Acad Sciences
The white matter architecture of the brain imparts a distinct signature on neuronal
coactivation patterns. Interregional projections promote synchrony among distant neuronal …