Major advances in pulmonary arterial hypertension, pulmonary hypertension (PH)
associated with lung disease, and chronic thromboembolic PH cast new light on the …

Cardiogenic shock is characterized by tissue hypoxia caused by circulatory failure arising
from inadequate cardiac output. In addition to treating the pathologic process causing …

Right‐sided heart failure and tricuspid regurgitation are common and strongly associated
with poor quality of life and an increased risk of heart failure hospitalizations and death …

Background In the phase 3 STELLAR trial, sotatercept, an investigational first-in-class activin
signalling inhibitor, demonstrated beneficial effects on 6-min walk distance and additional …

Background In the early literature, unintentional vitamin C deficiency in humans was
associated with heart failure. Experimental vitamin C deficiency in guinea pigs caused …

Traditionally, congestive heart failure (HF) was phenotyped by echocardiography or other
imaging techniques according to left ventricular (LV) ejection fraction (LVEF). The more …

Background Limited data exist to characterize novel measures of right ventricular (RV)
function and the coupling to pulmonary circulation in patients with heart failure and …

Despite advances in medical therapy for patients with stage C heart failure (HF), survival for
patients with advanced HF is< 20% at 5 years. Durable left ventricular assist device (dLVAD) …

Severe tricuspid regurgitation (TR) is a progressive condition associated with substantial
morbidity, poor quality of life, and increased mortality. Patients with TR commonly have …

The increasing recognition of the right ventricle (RV) necessitates the development of RV-
focused interventions, devices and testbeds. In this study, we developed a soft robotic model …