[HTML][HTML] Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders

MMJ Van den Berg, J Krauskopf, JG Ramaekers… - Progress in …, 2020 - Elsevier
Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …

A literature review of traumatic brain injury biomarkers

HS Ghaith, AA Nawar, MD Gabra… - Molecular …, 2022 - Springer
Research into TBI biomarkers has accelerated rapidly in the past decade owing to the
heterogeneous nature of TBI pathologies and management, which pose challenges to TBI …

The potential of endurance exercise-derived exosomes to treat metabolic diseases

A Safdar, A Saleem, MA Tarnopolsky - Nature Reviews Endocrinology, 2016 - nature.com
Endurance exercise-mediated multisystemic adaptations are known to mitigate metabolism-
related disorders such as obesity and type 2 diabetes mellitus (T2DM). However, the …

[HTML][HTML] Are circulating microRNAs peripheral biomarkers for Alzheimer's disease?

S Kumar, PH Reddy - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2016 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss, multiple cognitive abnormalities and intellectual impairments. Currently, there …

A rigorous method to enrich for exosomes from brain tissue

LJ Vella, BJ Scicluna, L Cheng… - Journal of …, 2017 - Taylor & Francis
Extracellular vesicles, including exosomes, are released by all cells, including those of the
nervous system. Capable of delivering lipid, protein and nucleic acids to both nearby and …

miR-128-3p is a novel regulator of vascular smooth muscle cell phenotypic switch and vascular diseases

FM Farina, IF Hall, S Serio, S Zani, M Climent… - Circulation …, 2020 - Am Heart Assoc
Rationale: MicroRNAs (miRNAs, miRs) are small noncoding RNAs that modulate gene
expression by negatively regulating translation of target genes. Although the role of several …

Neural stem cell differentiation into mature neurons: mechanisms of regulation and biotechnological applications

MS Vieira, AK Santos, R Vasconcellos… - Biotechnology …, 2018 - Elsevier
The abilities of stem cells to self-renew and form different mature cells expand the
possibilities of applications in cell-based therapies such as tissue recomposition in …

MicroRNAs dysregulation and mitochondrial dysfunction in neurodegenerative diseases

M Catanesi, M d'Angelo, MG Tupone… - International Journal of …, 2020 - mdpi.com
Neurodegenerative diseases are debilitating and currently incurable conditions causing
severe cognitive and motor impairments, defined by the progressive deterioration of …

Exosomes as mediators of the systemic adaptations to endurance exercise

A Safdar, MA Tarnopolsky - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Habitual endurance exercise training is associated with multisystemic metabolic adaptations
that lower the risk of inactivity-associated disorders such as obesity and type 2 diabetes …

Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration

W Huang, Y Feng, J Liang, H Yu, C Wang… - Nature …, 2018 - nature.com
The goal of replenishing the cardiomyocyte (CM) population using regenerative therapies
following myocardial infarction (MI) is hampered by the limited regeneration capacity of adult …