K Bhandari, WQ Ding - International Journal of Molecular Sciences, 2024 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignant disease with a low 5-year overall survival rate. It is the third-leading cause of cancer-related deaths in the United …
T Passang, S Wang, H Zhang, F Zeng, PC Hsu… - Cancer Research, 2024 - AACR
Pancreatic cancer (PDAC) harbors a complex tumor microenvironment (TME), and crosstalk between cells in the TME can contribute to drug resistance and relapse. Vasoactive …
S Jafari, H Motedayyen, P Javadi, K Jamali… - Frontiers in …, 2024 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is among the most penetrative malignancies affecting humans, with mounting incidence prevalence worldwide. This cancer is usually not …
DJ Jiménez, A Javed, T Rubio-Tomás… - International Journal of …, 2024 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related death worldwide. It is commonly diagnosed in advanced stages and therapeutic …
C Chen, L Demirkhanyan, CS Gondi - Cells, 2024 - mdpi.com
With the lack of specific signs and symptoms, pancreatic ductal adenocarcinoma (PDAC) is often diagnosed at late metastatic stages, resulting in poor survival outcomes. Among …
F Scianò, F Terrana, C Pecoraro, B Parrino… - Future Medicinal …, 2024 - Taylor & Francis
Pancreatic ductal adenocarcinoma (PDAC) is among the leading causes of cancer-related deaths worldwide. Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase often …
A Bararia, A Das, S Mitra, S Banerjee… - World journal of …, 2023 - ncbi.nlm.nih.gov
Pancreatic cancer (PanCa) presents a catastrophic disease with poor overall survival at advanced stages, with immediate requirement of new and effective treatment options …
C Ren, Y Wang, X Yang, Y Tuo, Y Li, J Gong - Heliyon, 2024 - cell.com
Immune checkpoint inhibitors have become one of the effective means of solid tumor treatment, among which anti-programmed death-1 (PD-1) antibodies are more maturely …
H Imai, Y Sakamoto, S Takahashi, H Shibata, A Sato… - BMC cancer, 2024 - Springer
Background Advanced pancreatic cancer is one of the leading causes of cancer-related deaths. For patients with advanced pancreatic cancer, gemcitabine and nanoparticle …