[HTML][HTML] Reciprocal regulation of mesenchymal stem cells and immune responses

Y Wang, J Fang, B Liu, C Shao, Y Shi - Cell stem cell, 2022 - cell.com
Mesenchymal stem/stromal cells (MSCs) exist in almost all tissues and participate in tissue
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …

Impact of cryopreservation and freeze-thawing on therapeutic properties of mesenchymal stromal/stem cells and other common cellular therapeutics

C Cottle, AP Porter, A Lipat, C Turner-Lyles… - Current stem cell …, 2022 - Springer
Abstract Purpose of Review Cryopreservation and its associated freezing and thawing
procedures–short “freeze-thawing”–are among the final steps in economically viable …

[HTML][HTML] Adverse events, side effects and complications in mesenchymal stromal cell-based therapies

DS Baranovskii, ID Klabukov… - Stem Cell …, 2022 - ncbi.nlm.nih.gov
Numerous clinical studies have shown a wide clinical potential of mesenchymal stromal
cells (MSCs) application. However, recent experience has accumulated numerous reports of …

Bone marrow-derived mesenchymal stromal cell therapy in severe COVID-19: preliminary results of a phase I/II clinical trial

C Grégoire, N Layios, B Lambermont… - Frontiers in …, 2022 - frontiersin.org
Background Treatment of acute respiratory distress syndrome (ARDS) associated with
COronaVIrus Disease-2019 (COVID-19) currently relies on dexamethasone and supportive …

Immunological priming of mesenchymal stromal/stem cells and their extracellular vesicles augments their therapeutic benefits in experimental graft-versus-host …

A Hackel, S Vollmer, K Bruderek, S Lang… - Frontiers in …, 2023 - frontiersin.org
Mesenchymal stromal cells (MSCs) and their extracellular vesicles (EVs) exert profound anti-
inflammatory and regenerative effects in inflammation and tissue damage, which makes …

Systematic review and meta-analysis of cell therapy for COVID-19: global clinical trial landscape, published safety/efficacy outcomes, cell product manufacturing and …

PS Couto, N Al-Arawe, IS Filgueiras… - Frontiers in …, 2023 - frontiersin.org
During the pandemic of severe respiratory distress syndrome coronavirus 2 (SARS-CoV2),
many novel therapeutic modalities to treat Coronavirus 2019 induced disease (COVID-19) …

An overview of current research on mesenchymal stem cell-derived extracellular vesicles: a bibliometric analysis from 2009 to 2021

X Zhang, Y Lu, S Wu, S Zhang, S Li… - Frontiers in Bioengineering …, 2022 - frontiersin.org
Background: Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) are important
mediators of intercellular communication and participate in numerous physiological and …

Adipose tissue-derived human mesenchymal stromal cells can better suppress complement lysis, engraft and inhibit acute graft-versus-host disease in mice

SCM Wu, M Zhu, SCC Chik, M Kwok, A Javed… - Stem Cell Research & …, 2023 - Springer
Background Acute graft-versus-host disease (aGvHD) is a life-threatening complication of
allogeneic hematopoietic stem cell transplantation (HSCT). Transplantation of …

Dynamic culture of mesenchymal stromal/stem cell spheroids and secretion of paracrine factors

P Fuentes, MJ Torres, R Arancibia… - … in Bioengineering and …, 2022 - frontiersin.org
In recent years, conditioned medium (CM) obtained from the culture of mesenchymal
stromal/stem cells (MSCs) has been shown to effectively promote tissue repair and modulate …

Role of mesenchymal stem/stromal cells in coagulation

R Guillamat-Prats - International journal of molecular sciences, 2022 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) are widely used in disease models in order to
control several phases in the response to injuries, immune reaction, wound healing, and …