2018 joint European consensus document on the management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or …

GYH Lip, JP Collet, M Haude, R Byrne, EH Chung… - Ep …, 2019 - academic.oup.com
In 2014, a joint consensus document dealing with the management of antithrombotic therapy
in atrial fibrillation (AF) patients presenting with acute coronary syndrome (ACS) and/or …

Current and future antiplatelet therapies: emphasis on preserving haemostasis

JD McFadyen, M Schaff, K Peter - Nature Reviews Cardiology, 2018 - nature.com
Antiplatelet drugs, such as aspirin, P2Y12 antagonists, and glycoprotein (GP) IIb/IIIa
inhibitors, have proved to be successful in reducing the morbidity and mortality associated …

[HTML][HTML] Ticagrelor with or without aspirin in high-risk patients after PCI

R Mehran, U Baber, SK Sharma… - … England Journal of …, 2019 - Mass Medical Soc
Background Monotherapy with a P2Y12 inhibitor after a minimum period of dual antiplatelet
therapy is an emerging approach to reduce the risk of bleeding after percutaneous coronary …

Effect of P2Y12 inhibitor monotherapy vs dual antiplatelet therapy on cardiovascular events in patients undergoing percutaneous coronary intervention: the SMART …

JY Hahn, YB Song, JH Oh, WJ Chun, YH Park… - Jama, 2019 - jamanetwork.com
Importance Data on P2Y12 inhibitor monotherapy after short-duration dual antiplatelet
therapy (DAPT) in patients undergoing percutaneous coronary intervention are limited …

Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin …

P Vranckx, M Valgimigli, P Jüni, C Hamm, PG Steg… - The Lancet, 2018 - thelancet.com
Background We hypothesised that ticagrelor, in combination with aspirin for 1 month,
followed by ticagrelor alone, improves outcomes after percutaneous coronary intervention …

[HTML][HTML] Ticagrelor in patients with stable coronary disease and diabetes

PG Steg, DL Bhatt, T Simon, K Fox… - New England journal …, 2019 - Mass Medical Soc
Background Patients with stable coronary artery disease and diabetes mellitus who have not
had a myocardial infarction or stroke are at high risk for cardiovascular events. Whether …

Ticagrelor alone vs. ticagrelor plus aspirin following percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndromes …

U Baber, G Dangas, DJ Angiolillo… - European heart …, 2020 - academic.oup.com
Aims The aim of this study was to determine the effect of ticagrelor monotherapy on clinically
relevant bleeding and major ischaemic events in relation to clinical presentation with and …

Ticagrelor monotherapy in patients at high bleeding risk undergoing percutaneous coronary intervention: TWILIGHT-HBR

J Escaned, D Cao, U Baber, J Nicolas… - European heart …, 2021 - academic.oup.com
Aims Patients at high bleeding risk (HBR) represent a prevalent subgroup among those
undergoing percutaneous coronary intervention (PCI). Early aspirin discontinuation after a …

Aspirin-free strategies in cardiovascular disease and cardioembolic stroke prevention

D Capodanno, R Mehran, M Valgimigli… - Nature Reviews …, 2018 - nature.com
In patients with manifestations of cardiovascular disease, acetylsalicylic acid (popularly
known as aspirin) has been the mainstay of treatment for decades owing to its capacity to …

Management of Antithrombotic Therapy in Atrial Fibrillation Patients Undergoing PCI: JACC State-of-the-Art Review

D Capodanno, K Huber, R Mehran, GYH Lip… - Journal of the American …, 2019 - jacc.org
Most patients with atrial fibrillation (AF) and risk factors for stroke require oral anticoagulation
(OAC) to decrease the risk of stroke or systemic embolism. This is now best achieved with …