Traditional Chinese medicine in the era of immune checkpoint inhibitor: theory, development, and future directions

Y Yu, S Wang, Z Liu, X Zhang, Z Hu, H Dong, X Lu… - Chinese Medicine, 2023 - Springer
Immune checkpoint inhibitors (ICIs) have revolutionized cancer management and have
been widely applied; however, they still have some limitations in terms of efficacy and …

[HTML][HTML] Macrophage-related therapeutic strategies: regulation of phenotypic switching and construction of drug delivery systems

X Wang, Y Li, X Pu, G Liu, H Qin, W Wan, Y Wang… - Pharmacological …, 2023 - Elsevier
Macrophages, as highly phenotypic plastic immune cells, play diverse roles in different
pathological conditions. Changing and controlling the phenotypes of macrophages is …

[HTML][HTML] Xuanfei Baidu formula alleviates impaired mitochondrial dynamics and activated NLRP3 inflammasome by repressing NF-κB and MAPK pathways in LPS …

Z Li, H Pan, J Yang, D Chen, Y Wang, H Zhang… - Phytomedicine, 2023 - Elsevier
Abstract Background Xuanfei Baidu Formula (XBF) is an effective traditional Chinese
medicine (TCM) remedy for treating coronavirus disease 2019 (COVID-19) in China. This …

BATMAN-TCM 2.0: an enhanced integrative database for known and predicted interactions between traditional Chinese medicine ingredients and target proteins

X Kong, C Liu, Z Zhang, M Cheng, Z Mei… - Nucleic Acids …, 2024 - academic.oup.com
Traditional Chinese medicine (TCM) is increasingly recognized and utilized worldwide.
However, the complex ingredients of TCM and their interactions with the human body make …

Magnetic liposome as a dual-targeting delivery system for idiopathic pulmonary fibrosis treatment

X Wang, Y Wang, Z Xue, W Wan, Y Li, H Qin… - Journal of Colloid and …, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is the most common form of idiopathic interstitial
pneumonia, where M2 macrophages play an irreplaceable role in the anti-inflammatory …

Xuanfei Baidu decoction attenuates intestinal disorders by modulating NF-κB pathway, regulating T cell immunity and improving intestinal flora

L Ma, X Zhao, T Liu, Y Wang, J Wang, L Kong, Q Zhao… - Phytomedicine, 2022 - Elsevier
Background A number of studies have shown that gastrointestinal manifestations co-exist
with respiratory symptoms in coronavirus disease 2019 (COVID-19) patients. Xuanfei Baidu …

Pharmacological effects and mechanism of Maxing Shigan decoction in the treatment of Pseudomonas aeruginosa pneumonia

Y Xu, L Bao, S Cao, B Pang, J Zhang, Y Zhang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Maxing Shigan Decoction (MXSG) is a traditional
Chinese Medicine effectively used in respiratory infections and bacterial pneumonia …

[HTML][HTML] Yangqing Chenfei formula attenuates silica-induced pulmonary fibrosis by suppressing activation of fibroblast via regulating PI3K/AKT, JAK/STAT, and Wnt …

F Yang, R Hou, X Liu, Y Tian, Y Bai, J Li, P Zhao - Phytomedicine, 2023 - Elsevier
Abstract Background Yangqing Chenfei formula (YCF) has been demonstrated its clinical
efficiency on silicosis patients. However, the effect of YCF against silicotic fibrosis and its …

Licochalcone A protects against LPS‐induced inflammation and acute lung injury by directly binding with myeloid differentiation factor 2 (MD2)

W Zhu, M Wang, L Jin, B Yang, B Bai… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Acute lung injury (ALI)/acute respiratory distress syndrome
(ARDS) is a challenging clinical syndrome that leads to various respiratory sequelae and …

Preparation of Budesonide-Loaded Liposomal Nanoparticles for Pulmonary Delivery and Their Therapeutic Effect in OVA-Induced Asthma in Mice

X Zuo, Y Gu, X Guo, W Zheng, H Zheng… - International journal …, 2024 - Taylor & Francis
Purpose Inhaled corticosteroids, including budesonide (BUD), are widely employed for the
treatment of asthma. However, the frequent use of corticosteroids is associated with …