Carbapenem resistance is a major global health problem that seriously compromises the
treatment of infections caused by nosocomial pathogens. Resistance to carbapenems …

β-lactam antibiotics (BLAs) are crucial molecules among antibacterial drugs, but the
increasing emergence of resistance to them, developed by bacteria producing β-lactamase …

New Delhi metallo-β-lactamase-1 (NDM-1) can hydrolyze almost all antibiotics of the β-
lactam group, resulting in the generation of multidrug resistant bacteria. Besides its broad …

Abstract β-lactamase are the main resistance factor for β-lactam antibiotics in Gram-negative
bacteria. Since β-lactam antibiotics are being utilised as an antimicrobial agents extensively …

The worldwide prevalence of NDM-1-producing Gram-negative pathogens has drastically
undermined the clinical efficacy of carbapenems, prompting a need to devise an effective …

The production of extended spectrum β-lactamases (ESBLs) in extensively drug-resistant
(XDR) strains of Acinetobacter baumannii has created havoc amongst clinicians making the …

Tissue engineering (TE), a fast-growing field of regenerative medicine, has been designed
to replace diseased or damaged tissues. As cellular factories, microbes produce a wide …

The past two decades have been marked by a global spread of bacterial resistance to β-
lactam drugs and carbapenems derivatives are the ultimate treatment against multidrug …

New Delhi Metallo-β-lactamase-1 (NDM-1) is the most prevalent type of metallo-β-
lactamase, able to hydrolyze almost all antibiotics of the β-lactam group, leading to multidrug …

为了解携带碳青霉烯酶NDM-1 及其亚型在猪场的流行情况, 对来自猪场产房仔猪腹泻病例分离
鉴定的87 株大肠杆菌进行了碳青霉烯酶NDM-1 和NDM-5 的耐药基因扩增及测序. 从87 …