Unexplained post-acute infection syndromes

J Choutka, V Jansari, M Hornig, A Iwasaki - Nature Medicine, 2022 - nature.com
SARS-CoV-2 is not unique in its ability to cause post-acute sequelae; certain acute
infections have long been associated with an unexplained chronic disability in a minority of …

A comprehensive review of risk factors for venous thromboembolism: from epidemiology to pathophysiology

D Pastori, VM Cormaci, S Marucci, G Franchino… - International Journal of …, 2023 - mdpi.com
Venous thromboembolism (VTE) is the third most common cause of death worldwide. The
incidence of VTE varies according to different countries, ranging from 1–2 per 1000 person …

D-dimer: old dogmas, new (COVID-19) tricks

G Lippi, F Mullier, EJ Favaloro - Clinical Chemistry and Laboratory …, 2023 - degruyter.com
D-dimer is a fibrin degradation product encompassing multiple cross-linked D domains
and/or E domains present in the original fibrinogen molecule, whose generation is only …

NLRP3 inflammasome and interleukin-1 contributions to COVID-19-associated coagulopathy and immunothrombosis

N Potere, E Garrad, Y Kanthi, M Di Nisio… - Cardiovascular …, 2023 - academic.oup.com
Immunothrombosis—immune-mediated activation of coagulation—is protective against
pathogens, but excessive immunothrombosis can result in pathological thrombosis and …

Chronic pulmonary manifestations of COVID-19 infection: imaging evaluation

MC Murphy, BP Little - Radiology, 2023 - pubs.rsna.org
This case presents a patient with severe COVID-19 pneumonia requiring intensive care unit
admission and a prolonged hospital stay. The infection resulted in long-term morbidity …

Inflammasome signaling, thromboinflammation, and venous thromboembolism

N Potere, A Abbate, Y Kanthi, M Carrier, S Toldo… - Basic to Translational …, 2023 - jacc.org
Venous thromboembolism (VTE) remains a major health burden despite anticoagulation
advances, suggesting incomplete management of pathogenic mechanisms. The NLRP3 …

The role of heparin in COVID-19: an update after two years of pandemics

M Mangiafico, A Caff, L Costanzo - Journal of Clinical Medicine, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is associated with an increased risk of venous
thromboembolism (VTE) and coagulopathy, especially in critically ill patients. Endothelial …

Risk of Thrombosis during and after a SARS-CoV-2 Infection: Pathogenesis, Diagnostic Approach, and Management

H Sutanto, G Soegiarto - Hematology Reports, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19) increases the risk of thromboembolic events,
especially in patients with severe infections requiring intensive care and cardiorespiratory …

Effectiveness and safety of extended thromboprophylaxis in post-discharge patients with COVID-19: A systematic review and meta-analysis

MF Dai, WX Xin, S Kong, HY Ding, L Fang - Thrombosis Research, 2023 - Elsevier
Background The effect of extended thromboprophylaxis in improving the prognosis of adult
patients with coronavirus disease 2019 (COVID-19) after discharge remains debatable. This …

Application of a decision tree model to predict the outcome of non-intensive inpatients hospitalized for COVID-19

M Giotta, P Trerotoli, VO Palmieri, F Passerini… - International Journal of …, 2022 - mdpi.com
Many studies have identified predictors of outcomes for inpatients with coronavirus disease
2019 (COVID-19), especially in intensive care units. However, most retrospective studies …