With aging, there is increased dysfunction of both innate and adaptive immune responses,
which contributes to impaired immune responses to pathogens and greater mortality and …

SARS-COV-2 infection represents the greatest pandemic of the world, counting daily
increasing number of subjects positive to the virus and, sadly, increasing number of deaths …

Abstract Pediatric Coronavirus Disease 2019 (pCOVID-19) is rarely severe; however, a
minority of children infected with severe acute respiratory syndrome coronavirus 2 (SARS …

COVID-19 exhibits extensive patient-to-patient heterogeneity. To link immune response
variation to disease severity and outcome over time, we longitudinally assessed circulating …

Summary Background Infections with SARS-CoV-2 continue to cause significant morbidity
and mortality. Interleukin (IL)-1 and IL-6 blockade have been proposed as therapeutic …

The molecular basis of the wide clinical heterogeneity of Coronavirus disease 2019 (COVID-
19) is still unknown. Matrix metalloproteinases (MMPs) may have a role in the lung damage …

Acute viral infections can have durable functional impacts on the immune system long after
recovery, but how they affect homeostatic immune states and responses to future …

Hypercytokinemia, found in SARS-CoV-2 infection, contributes to multiple organ
dysfunctions with acute respiratory distress syndrome, shock etc. The aim of this study was …

Background Thromboembolism is a life-threatening manifestation of coronavirus disease
2019 (COVID-19). We investigated a dysfunctional phenotype of vascular endothelial cells …

The COVID-19 pandemic is spreading around the world and 187 million people have
already been affected. One of its after-effects is post-COVID depression, which, according to …