During peritoneal dialysis, peritoneal cells are repeatedly exposed to a non-physiological hypertonic environment with high glucose content and low pH. Current sterile dialysis …
JC Fox, T Nakayama, RC Tyler, TL Sander, O Yoshie… - Cytokine, 2015 - Elsevier
Known for its unusual metamorphic native state structure, XCL1 has been the focus of most efforts to elucidate the structural, functional, and physiological properties of chemokines in …
M Kitamura - Seminars in immunopathology, 2013 - Springer
Endoplasmic reticulum (ER) stress and consequent unfolded protein response (UPR) are involved in a diverse range of pathologies including ischemic diseases, neurodegenerative …
P Sosińska, E Baum, B Maćkowiak… - American Journal of …, 2016 - ncbi.nlm.nih.gov
Peritoneal mesothelial cells exposed to bioincompatible dialysis fluids contribute to damage of the peritoneum during chronic dialysis. Inflammatory response triggered in the …
RJFC do Amaral, KD Arcanjo, MC El-Cheikh… - Cells Tissues …, 2017 - karger.com
There are several pathologies associated with the peritoneum, such as mesothelioma and peritonitis. Moreover, the peritoneum is widely used in ultrafiltration procedures, ie …
T Dai, Y Wang, A Nayak, CC Nast, L Quang… - Kidney International, 2014 - Elsevier
Peritoneal membrane pathology limits long-term peritoneal dialysis (PD). Here, we tested whether JAK/STAT signaling is implicated and if its attenuation might be salutary. In cultured …
H Johno, R Ogata, S Nakajima… - Nephrology Dialysis …, 2012 - academic.oup.com
Background Bacterial peritonitis is a frequent complication in patients on peritoneal dialysis (PD). We previously reported that PD fluid (PDF) suppressed expression of monocyte …
A Riesenhuber, K Kratochwill… - Peritoneal dialysis …, 2011 - journals.sagepub.com
Background Noninfectious upregulation of proinflammatory pathways in mesothelial cells may represent an integral part of their stress response upon exposure to peritoneal dialysis …