Balanced crystalloids versus saline in critically ill adults—a systematic review with meta-analysis
Background The comparative efficacy and safety of balanced crystalloid solutions and saline
for fluid therapy in critically ill adults remain uncertain. Methods We systematically reviewed …
for fluid therapy in critically ill adults remain uncertain. Methods We systematically reviewed …
Management of acute upper gastrointestinal bleeding
AJ Stanley, L Laine - Bmj, 2019 - bmj.com
Upper gastrointestinal bleeding (UGIB) is a common medical emergency, with a reported
mortality of 2-10%. Patients identified as being at very low risk of either needing an …
mortality of 2-10%. Patients identified as being at very low risk of either needing an …
Effect of continuous infusion of hypertonic saline vs standard care on 6-month neurological outcomes in patients with traumatic brain injury: the COBI randomized …
Importance Fluid therapy is an important component of care for patients with traumatic brain
injury, but whether it modulates clinical outcomes remains unclear. Objective To determine …
injury, but whether it modulates clinical outcomes remains unclear. Objective To determine …
Clinical implications and challenges of artificial intelligence and deep learning
WW Stead - Jama, 2018 - jamanetwork.com
Artificial intelligence (AI) and deep learning are entering the mainstream of clinical medicine.
For example, in December 2016, Gulshan et al1 reported development and validation of a …
For example, in December 2016, Gulshan et al1 reported development and validation of a …
[HTML][HTML] Intravenous fluid therapy in critically ill adults
Intravenous fluid therapy is one of the most common interventions in acutely ill patients.
Each day, over 20% of patients in intensive care units (ICUs) receive intravenous fluid …
Each day, over 20% of patients in intensive care units (ICUs) receive intravenous fluid …
Balanced crystalloids versus saline in sepsis. A secondary analysis of the SMART clinical trial
Rationale: Administration of intravenous crystalloid solutions is a fundamental therapy for
sepsis, but the effect of crystalloid composition on patient outcomes remains unknown …
sepsis, but the effect of crystalloid composition on patient outcomes remains unknown …
[HTML][HTML] Endothelial glycocalyx degradation in critical illness and injury
The endothelial glycocalyx is a gel-like layer on the luminal side of blood vessels that is
composed of glycosaminoglycans and the proteins that tether them to the plasma …
composed of glycosaminoglycans and the proteins that tether them to the plasma …
Perioperative fluid therapy for major surgery
Perioperative Fluid Therapy for Major Surgery | Anesthesiology | American Society of
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Balanced crystalloid solution versus saline in deceased donor kidney transplantation (BEST-Fluids): a pragmatic, double-blind, randomised, controlled trial
Background Delayed graft function (DGF) is a major adverse complication of deceased
donor kidney transplantation. Intravenous fluids are routinely given to patients receiving a …
donor kidney transplantation. Intravenous fluids are routinely given to patients receiving a …
Acute kidney injury
Acute kidney injury (AKI) is defined by a rapid increase in serum creatinine, decrease in
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …