Biological age (BA) is important for clinical monitoring and preventing aging-related
disorders and disabilities. Clinical and/or cellular biomarkers are measured and integrated …

Polygenic inheritance is a non-Mendelian form of inheritance in which the risk of a trait,
disorder, or disease results from the combined contribution of variants from multiple genes …

Polygenic scores (PGS) enable the prediction of genetic predisposition for a wide range of
traits and diseases by calculating the weighted sum of allele dosages for genetic variants …

Abstract Polygenetic Risk Scores are used to evaluate an individual's vulnerability to
developing specific diseases or conditions based on their genetic composition, by taking …

We aimed to identify potential novel predictors for breast cancer among post-menopausal
women, with pre-specified interest in the role of polygenic risk scores (PRS) for risk …

Background The popular statistics-based Genome-wide association studies (GWAS) have
provided deep insights into the field of complex disorder genetics. However, its clinical …

Abstract Background and Aims The association of serum uric acid (SUA) levels with liver‐
related morbidity and mortality remains undetermined. Therefore, we aimed to explore the …

Context This study aimed to investigate the association between night shift work and the risk
of nonalcoholic fatty liver disease (NAFLD). Methods We conducted a prospective analysis …

Metformin is a widely used and effective medication in type 2 diabetes (T2DM) as well as in
polycystic ovary syndrome (PCOS). Single nucleotide polymorphisms (SNPs) contribute to …

The D2 dopamine receptor (D2R) is the primary site of the therapeutic action of
antipsychotics and is involved in essential brain functions relevant to schizophrenia, such as …