Globally, the prevalence of obesity is increasing which subsequently increases the risk of
the development of obesity-related chronic diseases. Low-grade chronic inflammation and …

Aromatase inhibitors are the preferred treatment for certain women with estrogen receptor
(ER)-positive breast cancer, but evidence suggests that women with obesity experience …

The incidence of obesity, a recognized risk factor for various metabolic and chronic
diseases, including numerous types of cancers, has risen dramatically over the recent …

Background To analyze the allelic variants of genes of enzymes involved in estrogen
metabolism: CYP1A1, CYP1A2, CYP19 and SULT1A1 using polymerase chain reaction …

Incidence of breast cancer is rising rapidly in Asia. Some breast cancer risk factors are
modifiable. We examined the impact of known breast cancer risk factors, including body …

Objectives: to describe the epidemiological and clinical profile of women with endometriosis
and to determine the association with the prognostic characteristics of the disease. Methods …

Context: It has been shown that breast tumor actively produces and metabolizes steroid
hormones. However, little is known about the possible mechanisms through which the …

Background Risk of screen-detected breast cancer mostly reflects inherent risk, while risk of
interval cancer reflects inherent risk and risk of masking (risk of the tumor not being detected …

Background: Adult weight gain is associated with increased risk of postmenopausal breast
cancer. Most previous studies are limited by using recalled or self-reported data, and it is not …

Abstract Background Estrogen (17β-estradiol) promotes the survival and proliferation of
breast cancer cells and its receptors represent important therapeutic targets. The cellular …