An autoimmune disease is defined as a clinical syndrome resulted from an instigation of
both T cell and B cell or individually, in the absence of any present infection or any sort of …

Profound and debilitating fatigue is the most common complaint reported among individuals
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …

Although some signs of inflammation have been reported previously in patients with myalgic
encephalomyelitis or chronic fatigue syndrome (ME/CFS), the data are limited and …

Many cancer patients suffer from severe fatigue when treated with chemotherapy or
radiotherapy; however, the etiology and pathogenesis of this kind of fatigue remains …

Mitochondrial disease refers to a heterogeneous group of disorders resulting in defective
cellular energy production due to abnormal oxidative phosphorylation (oxphos). Primary …

Adult hippocampal neurogenesis is involved in memory and learning, and disrupted
neurogenesis is implicated in cognitive impairment and mood disorders, including anxiety …

Chemotherapy treatment negatively affects the nervous and immune systems and alters
gastrointestinal function and microbial composition. Outside of the cancer field, alterations in …

Background: The blood–brain barrier acts as a highly regulated interface; its dysfunction
may exacerbate, and perhaps initiate, neurological and neuropsychiatric disorders …

Ferroptosis is a unique form of programmed death, characterised by cytosolic accumulation
of iron, lipid hydroperoxides and their metabolites, and effected by the fatal peroxidation of …

Liver fibrosis is characterised by excessive deposition of extracellular matrix that interrupts
normal liver functionality. It is a pathological stage in several untreated chronic liver …