Research and therapeutic approaches in stem cell genome editing by CRISPR toolkit

B Mollashahi, H Latifi-Navid, I Owliaee, S Shamdani… - Molecules, 2023 - mdpi.com
The most widely used genome editing toolkit is CRISPR (clustered regularly interspaced
short palindromic repeats). It provides the possibility of replacing and modifying DNA and …

Kidney organoids reveal redundancy in viral entry pathways during ACE2-dependent SARS-CoV-2 infection

JM Vanslambrouck, JA Neil, R Rudraraju… - Journal of …, 2024 - Am Soc Microbiol
With a high incidence of acute kidney injury among hospitalized COVID-19 patients,
considerable attention has been focussed on whether SARS-CoV-2 specifically targets …

Modelling the viral dynamics of the SARS-CoV-2 Delta and Omicron variants in different cell types

CP McCormack, AWC Yan… - Journal of the …, 2023 - royalsocietypublishing.org
We use viral kinetic models fitted to viral load data from in vitro studies to explain why the
SARS-CoV-2 Omicron variant replicates faster than the Delta variant in nasal cells, but …