Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta …

F De Crescenzo, GL D'Alò, EG Ostinelli, M Ciabattini… - The Lancet, 2022 - thelancet.com
Background Behavioural, cognitive, and pharmacological interventions can all be effective
for insomnia. However, because of inadequate resources, medications are more frequently …

Management of Insomnia

CM Morin, DJ Buysse - New England Journal of Medicine, 2024 - Mass Medical Soc
Key Points Treatment Approaches to Insomnia Insomnia is common, and it frequently occurs
when other medical, psychiatric, and other sleep disorders are present. Persistent insomnia …

[PDF][PDF] Sleep and sleep disorders 2 insomnia

ML Perlis, D Posner, D Riemann, CH Bastien, J Teel… - Lancet, 2022 - unmfm.pbworks.com
Insomnia is highly prevalent in clinical practice, occurring in up to 50% of primary care
patients. Insomnia can present independently or alongside other medical conditions or …

Systems Biology in Cancer Diagnosis Integrating Omics Technologies and Artificial Intelligence to Support Physician Decision Making

A Fawaz, A Ferraresi, C Isidoro - Journal of Personalized Medicine, 2023 - mdpi.com
Cancer is the second major cause of disease-related death worldwide, and its accurate
early diagnosis and therapeutic intervention are fundamental for saving the patient's life …

[PDF][PDF] Common sleep disorders affecting older adults

EE Jaqua, M Hanna, W Labib… - The Permanente …, 2023 - thepermanentejournal.org
Sleep disorders in older adults increase with aging, likely due to increased sleep latency,
decreased sleep efficiency, and total sleep time. Common sleep issues include chronic …

Evaluation and management of insomnia in the clinical practice in Italy: a 2023 update from the Insomnia Expert Consensus Group

L Palagini, R Manni, C Liguori, L De Gennaro… - Journal of …, 2024 - Springer
Background Insomnia is the most reported sleep disorder in industrialized countries,
affecting, in the chronic form, around 10% of the European population. In Italy, such a …

Pharmacotherapeutic management of insomnia and effects on sleep processes, neural plasticity, and brain systems modulating stress: A narrative review

L Palagini, C Bianchini - Frontiers in neuroscience, 2022 - frontiersin.org
Introduction Insomnia is a stress-related sleep disorder, may favor a state of allostatic
overload impairing brain neuroplasticity, stress immune and endocrine pathways, and may …

Insomnia: pharmacologic treatment

BX Lou, M Oks - Clinics in geriatric medicine, 2021 - geriatric.theclinics.com
Insomnia has weighed heavily on the minds of many, including Shakespeare, who laments
“O sleep, O gentle sleep, Nature's soft nurse, how have I frightened thee?” 1 Although …

Benzodiazepine use and risk of incident MCI and dementia in a community sample

EG Teverovsky, A Gildengers, X Ran… - International …, 2024 - cambridge.org
Objectives: Older adults commonly take benzodiazepines (BZDs) that may have long-term
adverse cognitive effects. We investigated whether BZD use was related to developing mild …

Comparative efficacy of hypnotics in young and middle-aged adults with insomnia: A systematic review and network meta-analysis

F Hasan, HC Lee, PY Chen, YH Wang, LT Yuliana… - Sleep and …, 2023 - Springer
Objective/background Insomnia is highly prevalent in modern society. However, the
hierarchical selection of hypnotics in young and middle-aged adults with insomnia remains …