[HTML][HTML] Exploring immune-related pathogenesis in lung injury: Providing new insights Into ALI/ARDS

J Zheng, Y Li, X Kong, J Guo - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) represent a
significant global burden of morbidity and mortality, with lung injury being the primary cause …

[HTML][HTML] Immunometabolism changes in fibrosis: from mechanisms to therapeutic strategies

L Feng, X Chen, Y Huang, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Immune cells are essential for initiating and developing the fibrotic process by releasing
cytokines and growth factors that activate fibroblasts and promote extracellular matrix …

Chicoric acid ameliorates sepsis-induced cardiomyopathy via regulating macrophage metabolism reprogramming

HJ Sun, GL Zheng, ZC Wang, Y Liu, N Bao, PX Xiao… - Phytomedicine, 2024 - Elsevier
Background Sepsis-related cardiac dysfunction is believed to be a primary cause of high
morbidity and mortality. Metabolic reprogramming is closely linked to NLRP3 inflammasome …

[HTML][HTML] Dachengqi decoction alleviates acute lung injury by suppressing HIF-1α-mediated glycolysis

L Shang, M Zhang, J Li, F Zhou, S Wang, L Chen… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Acute lung injury (ALI) is an aggressive inflammatory
disease of the lungs characterized by a high mortality rate. More and more researchers have …

Machine learning‐based identification of cuproptosis‐related markers and immune infiltration in severe community‐acquired pneumonia

S Chen, Z Zhou, Y Wang, S Chen… - The Clinical Respiratory …, 2023 - Wiley Online Library
Background Severe community‐acquired pneumonia (SCAP) is one of the world's most
common diseases and a major etiology of acute respiratory distress syndrome (ARDS) …

[HTML][HTML] Research on pachymaran to ameliorate csA-Induced immunosuppressive lung injury by regulating microflora metabolism

C Ye, ZH Gao, KQ Chen, FG Lu, K Wei - Microorganisms, 2023 - mdpi.com
Pachymaran (PCP), the major medicinal constituent of Poria cocos, has a regulatory effect
on immunosuppressive lung injury, but its mechanism of action with respect to gut …

[HTML][HTML] Sulforaphane impedes mitochondrial reprogramming and histone acetylation in polarizing M1 (LPS) macrophages

S Bahiraii, M Brenner, W Weckwerth… - Free Radical Biology and …, 2024 - Elsevier
M1 (LPS) macrophages are characterized by a high expression of pro-inflammatory
mediators, and distinct metabolic features that comprise increased glycolysis, a broken TCA …

[HTML][HTML] Qi-Dong-Huo-Xue-Yin balances the immune microenvironment to protect against LPS induced acute lung injury

T Zhao, L Wang, Y Zhang, W Ye, J Liu, H Wu… - Frontiers in …, 2023 - frontiersin.org
COVID-19 induces acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) and
leads to severe immunological changes that threatens the lives of COVID-19 victims. Studies …

[HTML][HTML] Metabolomic characterization benefits the identification of acute lung injury in patients with type A acute aortic dissection

L Fan, K Meng, F Meng, Y Wu, L Lin - Frontiers in Molecular …, 2023 - ncbi.nlm.nih.gov
Introduction: Acute aortic dissection (AAD) often leads to the development of acute lung
injury (ALI). However, the early detection and diagnosis of AAD in patients with ALI pose …

Targeting reprogrammed metabolism as a therapeutic approach for respiratory diseases

PXL Gan, S Zhang, WSF Wong - Biochemical Pharmacology, 2024 - Elsevier
Metabolic reprogramming underlies the etiology and pathophysiology of respiratory
diseases such as asthma, idiopathic pulmonary fibrosis (IPF), and chronic obstructive …