Immunometabolic reprogramming of macrophages with inhalable CRISPR/Cas9 nanotherapeutics for acute lung injury intervention
W Huang, G Fu, Y Wang, C Chen, Y Luo, Q Yan, Y Liu… - Acta Biomaterialia, 2024 - Elsevier
Acute lung injury (ALI) represents a critical respiratory condition typified by rapid-onset lung
inflammation, contributing to elevated morbidity and mortality rates. Central to ALI …
inflammation, contributing to elevated morbidity and mortality rates. Central to ALI …
Machine learning‐based identification of cuproptosis‐related markers and immune infiltration in severe community‐acquired pneumonia
S Chen, Z Zhou, Y Wang, S Chen… - The Clinical Respiratory …, 2023 - Wiley Online Library
Background Severe community‐acquired pneumonia (SCAP) is one of the world's most
common diseases and a major etiology of acute respiratory distress syndrome (ARDS) …
common diseases and a major etiology of acute respiratory distress syndrome (ARDS) …
Taking advantage of the interaction between the sulfoxide and heme cofactor to develop indoleamine 2, 3-dioxygenase 1 inhibitors
Y Wang, S Jia, Y Chen, X Liao, R Jie, L Jiang… - Bioorganic …, 2024 - Elsevier
Taking advantage of key interactions between sulfoxide and heme cofactor, we used the
sulfoxide as the anchor functional group to develop two series of indoleamine 2, 3 …
sulfoxide as the anchor functional group to develop two series of indoleamine 2, 3 …
[HTML][HTML] Qi-Dong-Huo-Xue-Yin balances the immune microenvironment to protect against LPS induced acute lung injury
T Zhao, L Wang, Y Zhang, W Ye, J Liu, H Wu… - Frontiers in …, 2023 - frontiersin.org
COVID-19 induces acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) and
leads to severe immunological changes that threatens the lives of COVID-19 victims. Studies …
leads to severe immunological changes that threatens the lives of COVID-19 victims. Studies …
[HTML][HTML] Deficiency of interleukin-19 exacerbates acute lung injury induced by intratracheal treatment of hydrochloric acid
K Nishiyama, J Horikoshi, T Maehara, M Tanaka… - Journal of …, 2024 - Elsevier
Abstract Interleukin (IL-19) belongs to the IL-10 family of cytokines and plays diverse roles in
inflammation, cell development, viral responses, and lipid metabolism. Acute lung injury …
inflammation, cell development, viral responses, and lipid metabolism. Acute lung injury …
ISIR and its human homolog gene AK131315 strengthen LPS-induced inflammation and acute lung injury by promoting TAK1-dependent NF-κB and MAPK signaling
T Sun, F Wang, J Li, W Wei, Y Wang, Z Tong… - International …, 2024 - Elsevier
Acute lung injury (ALI), a critical complication observed in various clinical disorders, is
characterized by widespread inflammation, neutrophil infiltration, and proinflammatory …
characterized by widespread inflammation, neutrophil infiltration, and proinflammatory …
[HTML][HTML] 炎症与氧化应激在急性肺损伤中的作用研究进展
朱钰珊， 彭学容， 范苏苏， 孙亚茹， 张旋 - Hans Journal of Biomedicine, 2023 - hanspub.org
急性肺损伤(ALI)/急性呼吸窘迫综合征(ARDS) 一种以肺实质弥漫性炎症和顽固性低氧血症为
特征的临床危重症疾病. 尽管近几年国内外对ALI/ARDS 进行深入研究, 但由于其病因复杂 …
特征的临床危重症疾病. 尽管近几年国内外对ALI/ARDS 进行深入研究, 但由于其病因复杂 …
Circulating levels of interleukins and lung cancer and its subtypes: A Mendelian randomization study
L Zhai, Y Wei, M Chen, A Zhang, J Luo, Y Zheng, L Gao… - 2024 - researchsquare.com
Background Interleukins (ILs) are closely linked to the pathogenesis of lung cancer (LC).
However, the precise causal relationship between them remains somewhat ambiguous. This …
However, the precise causal relationship between them remains somewhat ambiguous. This …