Defining the role of natural killer cells in COVID-19

MJ Lee, CA Blish - Nature immunology, 2023 - nature.com
Natural killer (NK) cells are critical effectors of antiviral immunity. Researchers have
therefore sought to characterize the NK cell response to coronavirus disease 2019 (COVID …

[HTML][HTML] Natural killer cells in SARS-CoV-2 infection: pathophysiology and therapeutic implications

C Di Vito, F Calcaterra, N Coianiz, S Terzoli… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …

A patient-centric modeling framework captures recovery from SARS-CoV-2 infection

H Ruffieux, AL Hanson, S Lodge, NG Lawler… - Nature …, 2023 - nature.com
The biology driving individual patient responses to severe acute respiratory syndrome
coronavirus 2 infection remains ill understood. Here, we developed a patient-centric …

Immune responses in mildly versus critically ill COVID-19 patients

H Nasrollahi, AG Talepoor, Z Saleh… - Frontiers in …, 2023 - frontiersin.org
The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …

The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update

SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …

SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2D

MJ Lee, MW Leong, A Rustagi, A Beck, L Zeng… - Cell reports, 2022 - cell.com
Natural killer (NK) cells are cytotoxic effector cells that target and lyse virally infected cells;
many viruses therefore encode mechanisms to escape such NK cell killing. Here, we …

Severe COVID-19 patients display hyper-activated NK cells and NK cell-platelet aggregates

B Malengier-Devlies, J Filtjens, K Ahmadzadeh… - Frontiers in …, 2022 - frontiersin.org
COVID-19 is characterised by a broad spectrum of clinical and pathological features. Natural
killer (NK) cells play an important role in innate immune responses to viral infections. Here …

[HTML][HTML] Impact of SARS-CoV-2 infection on the profiles and responses of innate immune cells after recovery

V Ruenjaiman, P Sodsai, P Kueanjinda… - Journal of Microbiology …, 2022 - Elsevier
Backgrounds SARS-CoV-2 infection results in a broad spectrum of clinical outcomes,
ranging from asymptomatic to severe symptoms and death. Most COVID-19 pathogenesis is …

Tissue injury and leukocyte changes in post-acute sequelae of SARS-CoV-2: review of 2833 post-acute patient outcomes per immune dysregulation and microbial …

MS Islam, Z Wang, M Abdel-Mohsen… - Journal of Leukocyte …, 2023 - academic.oup.com
A significant number of persons with coronavirus disease 2019 (COVID-19) experience
persistent, recurrent, or new symptoms several months after the acute stage of severe acute …

Eight weeks of daily cannabidiol supplementation improves sleep quality and immune cell cytotoxicity

JN Kisiolek, VA Flores, A Ramani, B Butler… - Nutrients, 2023 - mdpi.com
Background: The endocannabinoid system is active in nervous and immune cells and
involves the expression of two cannabinoid receptor genes (CB1 and CB2), along with …