[HTML][HTML] Inflammation and tumor progression: signaling pathways and targeted intervention

H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

[HTML][HTML] Macrophage polarity and disease control

S Kadomoto, K Izumi, A Mizokami - International journal of molecular …, 2021 - mdpi.com
Macrophages are present in most human tissues and have very diverse functions. Activated
macrophages are usually divided into two phenotypes, M1 macrophages and M2 …

Stem cell therapy for COVID‐19, ARDS and pulmonary fibrosis

Z Li, S Niu, B Guo, T Gao, L Wang, Y Wang… - Cell …, 2020 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is an acute respiratory infectious disease
caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). COVID‐19 …

The cytokine storms of COVID-19, H1N1 influenza, CRS and MAS compared. Can one sized treatment fit all?

G Morris, CC Bortolasci, BK Puri, W Marx, A O'Neil… - Cytokine, 2021 - Elsevier
An analysis of published data appertaining to the cytokine storms of COVID-19, H1N1
influenza, cytokine release syndrome (CRS), and macrophage activation syndrome (MAS) …

[HTML][HTML] Obesity and its impact on COVID-19

AJM de Leeuw, MAM Oude Luttikhuis… - Journal of Molecular …, 2021 - Springer
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has proven
a challenge to healthcare systems since its first appearance in late 2019. The global spread …

[HTML][HTML] Macrophage biomimetic nanocarriers for anti-inflammation and targeted antiviral treatment in COVID-19

Q Tan, L He, X Meng, W Wang, H Pan, W Yin… - Journal of …, 2021 - Springer
Background The worldwide pandemic of COVID-19 remains a serious public health menace
as the lack of efficacious treatments. Cytokine storm syndrome (CSS) characterized with …

[HTML][HTML] Modulation of macrophage polarization by viruses: turning off/on host antiviral responses

S Yu, H Ge, S Li, HJ Qiu - Frontiers in microbiology, 2022 - frontiersin.org
Macrophages are professional antigen-presenting cells and serve as the first line of defense
against invading pathogens. Macrophages are polarized toward the proinflammatory …

Abatacept, cenicriviroc, or infliximab for treatment of adults hospitalized with COVID-19 pneumonia: a randomized clinical trial

JA O'Halloran, ER Ko, KJ Anstrom, E Kedar… - JAMA, 2023 - jamanetwork.com
Importance Immune dysregulation contributes to poorer outcomes in COVID-19. Objective
To investigate whether abatacept, cenicriviroc, or infliximab provides benefit when added to …

[HTML][HTML] Clinical aspects and presumed etiology of multisystem inflammatory syndrome in children (MIS-C): A review

A Kundu, S Maji, S Kumar, S Bhattacharya… - … and Global Health, 2022 - Elsevier
The COVID-19 outbreak sparked by SARS-CoV-2, begat significant rates of malady
worldwide, where children with an abnormal post-COVID ailment called the Multisystem …

[HTML][HTML] Upregulating human cathelicidin antimicrobial peptide LL-37 expression may prevent severe COVID-19 inflammatory responses and reduce microthrombosis

KM Aloul, JE Nielsen, EB Defensor, JS Lin… - Frontiers in …, 2022 - frontiersin.org
COVID-19 is characterized by hyperactivation by inflammatory cytokines and recruitment of
macrophages, neutrophils, and other immune cells, all hallmarks of a strong inflammatory …