Although the range of immune responses to severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) is variable, cytokine storm is observed in a subset of symptomatic …

ABSTRACT Background Coronavirus disease 2019 (COVID-19), an acute, sometimes
severe respiratory illness caused by a novel coronavirus has led to a vast pandemic with an …

Viral antigens are already known to be potential triggers of SLE. Few reports theorized that
SARS-CoV-2 could also be implicated in the SLE pathogenesis. 1 A 25-year-old female …

This study aims to assess anakinra's safety and efficacy for treating severe coronavirus
disease 2019 (COVID-19). Numerous electronic databases were searched and finally 15 …

Nowadays, people have relaxed their vigilance against COVID-19 due to its declining
infection numbers and attenuated virulence. However, COVID-19 still needs to be concern …

Since the end of 2019, a new, dangerous virus has caused the deaths of more than 3 million
people. Efforts to fight the disease remain multifaceted and include prophylactic strategies …

Single-cell RNA sequencing of the bronchoalveolar lavage fluid (BALF) samples from
COVID-19 patients has enabled us to examine gene expression changes of human tissue in …

PARP14 and PARP9 play a key role in macrophage immune regulation. SARS‐CoV‐2 is an
emerging viral disease that triggers hyper‐inflammation known as a cytokine storm. In this …

A hallmark of sterile and nonsterile inflammation is the increased accumulation of
cytoplasmic lipid droplets (LDs) in non-adipose cells. LDs are ubiquitous organelles …

During pregnancy, a series of physiological changes are determined at the molecular,
cellular and macroscopic level that make the mother and fetus more susceptible to certain …