Host factors in coronavirus replication
AH De Wilde, EJ Snijder, M Kikkert… - Roles of host gene and …, 2018 - Springer
Coronaviruses are pathogens with a serious impact on human and animal health. They
mostly cause enteric or respiratory disease, which can be severe and life threatening, eg, in …
mostly cause enteric or respiratory disease, which can be severe and life threatening, eg, in …
T-cell immunity of SARS-CoV: Implications for vaccine development against MERS-CoV
Over 12 years have elapsed since severe acute respiratory syndrome (SARS) triggered the
first global alert for coronavirus infections. Virus transmission in humans was quickly halted …
first global alert for coronavirus infections. Virus transmission in humans was quickly halted …
[HTML][HTML] Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals
L Ni, F Ye, ML Cheng, Y Feng, YQ Deng, H Zhao… - Immunity, 2020 - cell.com
Summary The World Health Organization has declared SARS-CoV-2 virus outbreak a
worldwide pandemic. However, there is very limited understanding on the immune …
worldwide pandemic. However, there is very limited understanding on the immune …
[HTML][HTML] Robust T cell response toward spike, membrane, and nucleocapsid SARS-CoV-2 proteins is not associated with recovery in critical COVID-19 patients
CJ Thieme, M Anft, K Paniskaki… - Cell Reports …, 2020 - cell.com
T cell immunity toward SARS-CoV-2 spike (S-), membrane (M-), and nucleocapsid (N-)
proteins may define COVID-19 severity. Therefore, we compare the SARS-CoV-2-reactive T …
proteins may define COVID-19 severity. Therefore, we compare the SARS-CoV-2-reactive T …
[HTML][HTML] Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding
The global outbreak of SARS in 2002-2003 was caused by the infection of a new human
coronavirus SARS-CoV. The infection of SARS-CoV is mediated mainly through the viral …
coronavirus SARS-CoV. The infection of SARS-CoV is mediated mainly through the viral …
[HTML][HTML] Peripheral CD4+ T cell subsets and antibody response in COVID-19 convalescent individuals
F Gong, Y Dai, T Zheng, L Cheng… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Marked progress is achieved in understanding the physiopathology of
coronavirus disease 2019 (COVID-19), which caused a global pandemic. However, the …
coronavirus disease 2019 (COVID-19), which caused a global pandemic. However, the …
Direct RNA nanopore sequencing of full-length coronavirus genomes provides novel insights into structural variants and enables modification analysis
Sequence analyses of RNA virus genomes remain challenging owing to the exceptional
genetic plasticity of these viruses. Because of high mutation and recombination rates …
genetic plasticity of these viruses. Because of high mutation and recombination rates …
Interaction of SARS and MERS coronaviruses with the antiviral interferon response
Abstract Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory
Syndrome (MERS) are the most severe coronavirus (CoV)-associated diseases in humans …
Syndrome (MERS) are the most severe coronavirus (CoV)-associated diseases in humans …
[HTML][HTML] Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy
The threat of a major coronavirus pandemic urges the development of strategies to combat
these pathogens. Human coronavirus NL63 (HCoV-NL63) is an α-coronavirus that can …
these pathogens. Human coronavirus NL63 (HCoV-NL63) is an α-coronavirus that can …
Blockade of the C5a–C5aR axis alleviates lung damage in hDPP4-transgenic mice infected with MERS-CoV
Y Jiang, G Zhao, N Song, P Li, Y Chen… - Emerging microbes & …, 2018 - Taylor & Francis
The pathogenesis of highly pathogenic Middle East respiratory syndrome coronavirus
(MERS-CoV) remains poorly understood. In a previous study, we established an hDPP4 …
(MERS-CoV) remains poorly understood. In a previous study, we established an hDPP4 …