Fibrosis results from excess extracellular matrix accumulation, which alters normal tissue
architecture and impedes function. In the salivary gland, fibrosis can be induced by …

C1q/tumor necrosis factor‐related protein‐6 (CTRP6) is a newly identified adipokine
involved in diverse biological processes. However, its role in salivary glands remains …

Proximal tubule (PT) transports most of the renal Ca 2+, which was usually described as
paracellular (passive). We found a regulated Ca 2+ entry pathway in PT cells via the apical …

Calcium phosphate (CaP) crystals, which begin to form in the early segments of the loop of
Henle (LOH), are known to act as precursors for calcium stone formation. The proximal …

Clinical studies and structural analyses of salivary stones strongly suggest a linkage
between higher saliva calcium (Ca2+) and salivary stone formation, sialolithiasis; however …

Proximal tubular (PT) acidosis, which alkalinizes the urinary filtrate, together with Ca2+
supersaturation in PT can induce luminal calcium phosphate (CaP) crystal formation. While …

Mucin (MUC) 8 has been shown to play an important role in respiratory disease and
inflammatory responses. In the present study, we investigated the question of whether …

Melamine, which induces proximal tubular (PT) cell damage has a greater nephrotoxic effect
when combined with cyanuric and uric acids; however, it is unknown whether such effect …

Sex differences in kidney stone formation are well known. Females generally have slightly
acidic blood and higher urine pH when compared with males, which makes them more …

In calcium nephrolithiasis (CaNL), most calcium kidney stones are identified as calcium
oxalate (CaOx) with variable amounts of calcium phosphate (CaP), where CaP is found as …