[HTML][HTML] Progress in research on the role of flavonoids in lung cancer

O Zanoaga, C Braicu, A Jurj, A Rusu, R Buiga… - International journal of …, 2019 - mdpi.com
Lung cancer is the leading cause of cancer deaths worldwide. Therefore, for the prevention,
diagnosis, prognosis and treatment of lung cancer, efficient preventive strategies and new …

Silibinin to improve cancer therapeutic, as an apoptotic inducer, autophagy modulator, cell cycle inhibitor, and microRNAs regulator

Z Jahanafrooz, N Motamed, B Rinner, A Mokhtarzadeh… - Life sciences, 2018 - Elsevier
Silibinin is a natural plant polyphenol with high antioxidant and anticancer properties, which
causes broad-spectrum efficacy against cancer, including cell cycle arrest and apoptosis in …

[HTML][HTML] Pro-oxidant and pro-apoptotic activity of polyphenol extract from Annurca apple and its underlying mechanisms in human breast cancer cells

S D'angelo, E Martino, CP Ilisso… - International …, 2017 - spandidos-publications.com
Among nutraceuticals, polyphenols represent the most intriguing and studied class of
compounds that can be therapeutics for a large spectrum of the most common diseases …

[HTML][HTML] Flavones: Six selected flavones and their related signaling pathways that induce apoptosis in cancer

SH Jeong, HH Kim, SE Ha, MY Park… - International Journal of …, 2022 - mdpi.com
Cancer is a horrific disease that, to date, has no cure. It is caused by various factors and
takes many lives. Apoptosis is a programmed cell death mechanism and if it does not …

Pharmacoinformatics approach for the identification of Polo-like kinase-1 inhibitors from natural sources as anti-cancer agents

MF AlAjmi, MT Rehman, A Hussain… - International journal of …, 2018 - Elsevier
Abstract Polo-like kinase-1 (PLK-1) plays a key role in cell cycle progression during mitosis.
Overexpression/dysfunction of PLK-1 is directly associated with cancerous transformation …

Natural products against cancer angiogenesis

EB Khalid, ELMELK Ayman, H Rahman, G Abdelkarim… - Tumor Biology, 2016 - Springer
The process of angiogenesis is quite well-known nowadays. Some medicines and extracts
affecting this process are already used routinely in supporting the conventional treatment of …

[HTML][HTML] Metabolomics and Molecular Networking to Characterize the Chemical Space of Four Momordica Plant Species

AT Ramabulana, D Petras, NE Madala, F Tugizimana - Metabolites, 2021 - mdpi.com
Momordica plant species (Cucurbitaceae), have been used for centuries in traditional
medicine and for nutritional purposes. Plants from this family are thus claimed to be …

Poziotinib and bovine serum albumin binding characterization and influence of quercetin, rutin, naringenin and sinapic acid on their binding interaction

S Zargar, S Alamery, AH Bakheit, TA Wani - Spectrochimica Acta Part A …, 2020 - Elsevier
Serum albumin is the major transporter protein present in systemic circulation and the ability
to transport ligands can be influenced in presence of other ligands. This interaction can …

[HTML][HTML] Modulation of multiple signaling pathways of the plant-derived natural products in cancer

L Sun, W Zhou, H Zhang, Q Guo, W Yang, B Li… - Frontiers in …, 2019 - frontiersin.org
Natural compounds are highly effective anticancer chemotherapeutic agents, and the targets
of plant-derived anticancer agents have been widely reported. In this review, we focus on …

Phenolic acids-versatile natural moiety with numerous biological applications

R Sehrawat, P Rathee, EK Akkol… - Current Topics in …, 2022 - ingentaconnect.com
Background: Medicinal uses of natural phenolic acids and their synthetic derivatives have
been augmented in recent years. Phenolic acids are chemically defined secondary plant …