[HTML][HTML] Flavonoids Luteolin and Quercetin Inhibit RPS19 and contributes to metastasis of cancer cells through c-Myc reduction

KC Chen, WH Hsu, JY Ho, CW Lin, CY Chu… - journal of food and drug …, 2018 - Elsevier
Flavonoids luteolin and quercetin can inhibit growth and metastasis of cancer cells. In our
previous report, luteolin and quercetin was shown to block Akt/mTOR/c-Myc signaling. Here …

Anti-cancer activity of catechin against A549 lung carcinoma cells by induction of cyclin kinase inhibitor P21 and suppression of cyclin E1 and P–AKT

H Sun, M Yin, D Hao, Y Shen - Applied Sciences, 2020 - mdpi.com
Catechin is one of the major polyphenols in teas, beans, and berry fruits. A number of
studies have confirmed that catechins extract possesses health benefits in the prevention of …

Bioactive compounds as an alternative for the sugarcane industry: Towards an integrative approach

A Molina-Cortés, M Quimbaya, A Toro-Gomez… - Heliyon, 2023 - cell.com
Here, a comprehensive review of sugarcane industrialization and its relationship with
bioactive compounds (BCs) detected in various products and by-products generated during …

Evaluation of inhibitory effects of flavonoids on breast cancer resistance protein (BCRP): From library screening to biological evaluation to structure-activity …

X Fan, J Bai, S Zhao, M Hu, Y Sun, B Wang, M Ji, J Jin… - Toxicology in Vitro, 2019 - Elsevier
Flavonoids are a group of polyphenols ubiquitously present in vegetables, fruits and herbal
products, despite various known pharmacological activities, few researches have been done …

Mitochondrial dysfunction in gliomas: pharmacotherapeutic potential of natural compounds

L Guntuku, VGM Naidu, VG Yerra - Current neuropharmacology, 2016 - ingentaconnect.com
Gliomas are the most common primary brain tumors either benign or malignant originating
from the glial tissue. Glioblastoma multiforme (GBM) is the most prevalent and aggressive …

Quercetin attenuates metastatic ability of human metastatic ovarian cancer cells via modulating multiple signaling molecules involved in cell survival, proliferation …

T Dhanaraj, M Mohan, J Arunakaran - Archives of Biochemistry and …, 2021 - Elsevier
Ovarian cancer is the most deadly gynaecology related cancer due to its high metastasizing
ability. Quercetin is the most abundant flavonoids received increased interest due to its anti …

Prunus lusitanica L. Fruits as a Novel Source of Bioactive Compounds with Antioxidant Potential: Exploring the Unknown

AS Abraão, N Fernandes, AM Silva… - Antioxidants, 2022 - mdpi.com
Prunus lusitanica L., also known as Portuguese laurel or locally known as 'azereiro', is a rare
species with ornamental and ecological value. Only two studies regarding the bioactivity and …

Molecular interaction studies on ellagic acid for its anticancer potential targeting pyruvate dehydrogenase kinase 3

R Dahiya, T Mohammad, P Gupta, A Haque… - RSC …, 2019 - pubs.rsc.org
Pyruvate dehydrogenase kinase 3 (PDK3) plays a central role in the cancer metabolic
switch through the reversible phosphorylation of pyruvate dehydrogenase complex thereby …

Defying multidrug resistance! Modulation of related transporters by flavonoids and flavonolignans

CS Chambers, J Viktorová… - Journal of agricultural …, 2019 - ACS Publications
Multidrug resistance (MDR) is a major challenge for the 21th century in both cancer
chemotherapy and antibiotic treatment of bacterial infections. Efflux pumps and transport …

Protective effect of daidzein against streptozotocin‐induced Alzheimer's disease via improving cognitive dysfunction and oxidative stress in rat model

J Wei, F Yang, C Gong, X Shi… - Journal of biochemical …, 2019 - Wiley Online Library
Oxidative stress is performing an essential role in developing Alzheimer's disease (AD), and
age‐related disorder and other neurodegenerative diseases. In existing research, we have …