Ferroptosis and its role in diverse brain diseases

A Weiland, Y Wang, W Wu, X Lan, X Han, Q Li… - Molecular …, 2019 - Springer
Ferroptosis is a recently identified, iron-regulated, non-apoptotic form of cell death. It is
characterized by cellular accumulation of lipid reactive oxygen species that ultimately leads …

Targeting ferroptosis to treat cardiovascular diseases: a new continent to be explored

F Huang, R Yang, Z Xiao, Y Xie, X Lin, P Zhu… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular diseases, including cardiomyopathy, myocardial infarction, myocardial
ischemia/reperfusion injury, heart failure, vascular injury, stroke, and arrhythmia, are …

Metabolomics and lipidomics of ischemic stroke

A Au - Advances in clinical chemistry, 2018 - Elsevier
Ischemic stroke is a sudden loss of brain function due to the reduction of blood flow. Brain
tissues cease to function with subsequent activation of the ischemic cascade. Metabolomics …

Apolipoprotein C-III in triglyceride-rich lipoprotein metabolism

B Ramms, PLSM Gordts - Current opinion in lipidology, 2018 - journals.lww.com
Novel in vivo models and APOC3 missense variants revealed unique mechanisms by which
apoC-III inhibits TRL catabolism. Clinical trials with Volanesorsen, an APOC3 antisense …

Mechanisms of ferritinophagy and ferroptosis in diseases

S Li, P Huang, F Lai, T Zhang, J Guan, H Wan… - Molecular …, 2024 - Springer
The discovery of the role of autophagy, particularly the selective form like ferritinophagy, in
promoting cells to undergo ferroptosis has inspired us to investigate functional connections …

[HTML][HTML] New perspectives on atherogenic dyslipidaemia and cardiovascular disease

AJ Lorenzatti, PP Toth - European Cardiology Review, 2020 - ncbi.nlm.nih.gov
Over the past few decades, atherogenic dyslipidaemia has become one of the most common
phenotypic presentations of lipid abnormalities, being strongly and unequivocally …

LncRNAs stand as potent biomarkers and therapeutic targets for stroke

J Fan, M Saft, N Sadanandan… - Frontiers in aging …, 2020 - frontiersin.org
Stroke is a major public health problem worldwide with a high burden of neurological
disability and mortality. Long noncoding RNAs (lncRNAs) have attracted much attention in …

Identification of signal pathways for immunotoxicity in the spleen of common carp exposed to chlorpyrifos

H Xing, J Chen, M Peng, Z Wang, F Liu, S Li… - … and Environmental Safety, 2019 - Elsevier
Chlorpyrifos (CPF) is an environmental pollutant due to its high toxicity to aquatic animals.
Because CPF was detected in aquatic environments in many countries, it has been widely …

A Novel Candidate for Prevention and Treatment of Atherosclerosis: Urolithin B Decreases Lipid Plaque Deposition in apoE−/− Mice and Increases Early Stages of …

W Zhao, L Wang, V Haller… - Molecular nutrition & food …, 2019 - Wiley Online Library
Scope HDL cholesterol is inversely related to the incidence of atherosclerosis. Polyphenols
including ellagitannins have been shown to exert antiatherogenic properties. Urolithin B is …

Genetic polymorphism detection of pathophysiological pathways of ischemic stroke in Asian

V Besin, T Yulianti, PB Notopuro, FM Humardani - Clinica Chimica Acta, 2023 - Elsevier
The increasing incidence of ischemic stroke emphasizes the necessity for early detection
and preventive strategies. Diagnostic biomarkers currently available for ischemic stroke only …