Co-encapsulation and release of apigenin and ascorbic acid in polyelectrolyte multilayer capsules for targeted polycystic ovary syndrome

S Nehru, A Guru, R Pachaiappan, AA Hatamleh… - International Journal of …, 2024 - Elsevier
Polycystic ovary syndrome (PCOS), a prevalent endocrine disorder in women of
reproductive age, is linked to hormonal imbalances and oxidative stress. Our study …

Butylparaben induced zebrafish (Danio rerio) kidney injury by down-regulating the PI3K-AKT pathway

L Huang, J Xu, K Jia, Y Wu, W Yuan, Z Liao… - Journal of Hazardous …, 2024 - Elsevier
Butylparaben, a common endocrine disruptor in the environment, is known to be toxic to the
reproductive system, heart, and intestines, but its nephrotoxicity has rarely been reported. In …

PS9, derived from an aquatic Fungus virulent protein, glycosyl hydrolase, arrests MCF-7 proliferation by regulating intracellular reactive oxygen species and apoptotic …

M Velayutham, P Sarkar, KM Karuppiah… - ACS …, 2023 - ACS Publications
One of the most common diseases in women is breast cancer, which has the highest death
globally. Surgery, chemotherapy, hormone treatments, and radiation are the current …

Synergetic effects of polyethylene microplastic and abamectin pesticides on the eyes of zebrafish larvae and adults through activation of apoptosis signaling pathways

A Guru, A Rady, NM Darwish, G Malafaia… - Environmental …, 2023 - Elsevier
Although the toxicity of microplastics (MPs) and pesticides has recently been described, the
possible effects of combining these pollutants are poorly understood. Thus, we evaluated …

Nanoplastic Exposure Mediates Neurodevelopmental Toxicity by Activating the Oxidative Stress Response in Zebrafish (Danio rerio)

X Cao, W Xie, M Feng, J Chen, J Zhang, J Luo… - ACS …, 2024 - ACS Publications
The global accumulation and adverse effects of nanoplastics (NPs) are a growing concern
for the environment and human health. In recent years, more and more studies have begun …

Aquatic Peptide: The Potential Anti-Cancer and Anti-Microbial Activity of GE18 Derived from Pathogenic Fungus Aphanomyces invadans

M Velayutham, PS Priya, P Sarkar, R Murugan… - Molecules, 2023 - mdpi.com
Small molecules as well as peptide-based therapeutic approaches have attracted global
interest due to their lower or no toxicity in nature, and their potential in addressing several …

Developmental toxicity and neurobehavioral effects of sodium selenite and selenium nanoparticles on zebrafish embryos

S Hariharan, S Chauhan, E Marcharla… - Aquatic Toxicology, 2024 - Elsevier
Selenium, a trace mineral, is essential for several physiological processes in humans and
animals. It is an antioxidant vital for the immunological response, DNA synthesis, thyroid …

Furan-based Chalcone Annihilates the Multi-Drug-Resistant Pseudomonas aeruginosa and Protects Zebra Fish Against its Infection

SPRR Nayak, C Basty, S Boopathi, LS Dhivya… - Journal of …, 2024 - Springer
The emergence of carbapenem-resistant Pseudomonas aeruginosa, a multi-drug-resistant
bacteria, is becoming a serious public health concern. This bacterium infects …

[HTML][HTML] Impacts of co-exposure to zearalenone and trifloxystrobin on the enzymatic activity and gene expression in zebrafish

T Cang, C Wu, C Chen, C Liu, W Song, Y Yu… - … and Environmental Safety, 2023 - Elsevier
Although humans and animals are usually exposed to combinations of toxic substances,
little is known about the interactive toxicity of mycotoxins and farm chemicals. Therefore, we …

Serine threonine-protein kinase-derived IW13 improves lipid metabolism via C/EBP-α/SREBP1/FAS signaling pathways in HFD-induced zebrafish in vivo larval model

A Guru, G Sudhakaran, SKR Namasivayam… - Applied Biochemistry …, 2023 - Springer
Obesity is linked to the development of major metabolic disorders such as type 2 diabetes,
cardiovascular disease, and cancer. Recent research has focused on the molecular link …