The role of dapagliflozin in the management of heart failure: an update on the emerging evidence

M Gupta, S Rao, G Manek, GC Fonarow… - … and clinical risk …, 2021 - Taylor & Francis
The burden and cost of heart failure management, primarily in the form of hospitalization in
the setting of decompensated heart failure, continue to be some of the biggest clinical …

Dapagliflozin: a review in symptomatic heart failure with reduced ejection fraction

HA Blair - American Journal of Cardiovascular Drugs, 2021 - Springer
Abstract Dapagliflozin [Farxiga®(USA); Forxiga®(EU)], a sodium–glucose cotransporter 2
(SGLT2) inhibitor, was recently approved in the USA and the EU for the treatment of adults …

Significance of Endothelial Dysfunction Amelioration for Sodium–Glucose Cotransporter 2 Inhibitor-Induced Improvements in Heart Failure and Chronic Kidney …

H Yanai, H Adachi, M Hakoshima, H Katsuyama - Metabolites, 2023 - mdpi.com
Beyond lowering plasma glucose levels, sodium–glucose cotransporter 2 inhibitors
(SGLT2is) significantly reduce hospitalization for heart failure (HF) and retard the …

[HTML][HTML] Comparative efficacy of sodium glucose cotransporter-2 inhibitors in the management of type 2 diabetes mellitus: A real-world experience

L Islam, D Jose, M Alkhalifah, D Blaibel… - World Journal of …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Sodium glucose cotransporter-2 inhibitors (SGLT-2i) are a class of drugs
with modest antidiabetic efficacy, weight loss effect, and cardiovascular benefits as proven …

[HTML][HTML] Comparative efficacy of dapagliflozin and empagliflozin of a fixed dose in heart failure: a network meta-analysis

Z Shi, F Gao, W Liu, X He - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Background: The efficacy of dapagliflozin and empagliflozin in Sodium-glucose Cotransport-
2 Inhibitors (SGLT-2i) in patients with heart failure (HF) has been discovered. However …

The risk of all-cause death with dapagliflozin versus placebo: a systematic review and meta-analysis of phase III randomized controlled trials

HB Chen, RS Meng, YL Yang, TH Yu - Expert Opinion on Drug …, 2023 - Taylor & Francis
Background Dapagliflozin has proven cardioprotective and nephroprotective effects.
However, the risk of all-cause death with dapagliflozin remains unclear. Research design …

Safety of sodium‐glucose cotransporter 2 inhibitors drugs among heart failure patients: a systematic review and meta‐analysis

H Soleimani, B Saeedian, Y Pasebani… - ESC Heart …, 2024 - Wiley Online Library
Abstract Sodium–glucose cotransporter‐2 inhibitors (SGLT2is) reduce morbidity and
mortality for heart failure (HF) patients and are recommended as cornerstones for their …

Adverse events and drug–drug interactions of sodium glucose co-transporter 2 inhibitors in patients treated for heart failure

C Stöllberger, J Finsterer… - Expert Review of …, 2023 - Taylor & Francis
Introduction Sodium glucose co-transporter 2-inhibitors (SGLT2-I), antihyperglycemic
agents, are increasingly prescribed in chronic heart failure (CHF). Their risk for drug–drug …

Efficacy of SGLT2 inhibitors in patients with heart failure: An overview of systematic reviews

A Sephien, M Ghobrial, T Reljic, X Prida… - International Journal of …, 2023 - Elsevier
Aims Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have been shown to have benefit
in patients with heart failure (HF). Multiple systematic reviews and meta-analyses (SRs and …

Insights into efficacy and safety of dapagliflozin treatment for the management in older adults with type 2 diabetes: a systematic review and meta-analysis

L Jiang, Y Jia, X Wang, Z Wang, X Lv, Y Jia… - Expert Opinion on …, 2023 - Taylor & Francis
Background This study aimed to evaluate the efficacy and safety of dapagliflozin as a
monotherapy glucose-lowering drug treatment for older adults with diabetes. Research …