Effects of acute and chronic arecoline in adult zebrafish: Anxiolytic-like activity, elevated brain monoamines and the potential role of microglia

N Serikuly, ET Alpyshov, DM Wang, JT Wang… - Progress in Neuro …, 2021 - Elsevier
Arecoline is a naturally occurring psychoactive alkaloid with partial agonism at nicotinic and
muscarinic acetylcholine receptors. Arecoline consumption is widespread, making it the …

[HTML][HTML] Bold zebrafish (Danio rerio) express higher levels of delta opioid and dopamine D2 receptors in the brain compared to shy fish

PO Thörnqvist, S McCarrick, M Ericsson… - Behavioural brain …, 2019 - Elsevier
Individual variation in coping with environmental challenges is a well-known phenomenon
across vertebrates, including teleost fish. Dopamine is the major transmitter in the brain …

The zebrafish for preclinical psilocybin research

O Syed, B Tsang, R Gerlai - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
In this review, we discuss the possible utility of zebrafish in research on psilocybin, a
psychedelic drug whose recreational use as well as possible clinical application are gaining …

Toxic effects of oxine-copper on development and behavior in the embryo-larval stages of zebrafish

H Wang, L Zhou, X Liao, Z Meng, J Xiao, F Li, S Zhang… - Aquatic Toxicology, 2019 - Elsevier
Oxine-copper (OxCu) is generally used as an agricultural pesticide and induces harmful
effects on ecosystems. In this study, zebrafish was used to assess the aquatic toxicity of …

Environmentally relevant concentrations of triclocarban affect behaviour, learning, and brain gene expression in fish

T Lucon-Xiccato, BB Savaşçı, C Merola… - Science of The Total …, 2023 - Elsevier
Many chemicals spilled in aquatic ecosystems can interfere with cognitive abilities and brain
functions that control fitness-related behaviour. Hence, their harmful potential may be …

Parkinson's disease model in zebrafish using intraperitoneal MPTP injection

NA Omar, J Kumar, SL Teoh - Frontiers in Neuroscience, 2023 - frontiersin.org
Introduction Parkinson's disease (PD) is the second most common neurodegenerative
disease that severely affects the quality of life of patients and their family members …

Cinnamaldehyde causes developmental neurotoxicity in zebrafish via the oxidative stress pathway that is rescued by astaxanthin

K Chang, N Zeng, Y Ding, X Zhao, C Gao, Y Li… - Food & function, 2022 - pubs.rsc.org
Toxicology studies provide a reliable dose range for the use of compounds. Zebrafish show
unique advantages in toxicology research. Cinnamaldehyde (Cin) is one of the main active …

Understanding autism and other neurodevelopmental disorders through experimental translational neurobehavioral models

JR Homberg, EJ Kyzar, M Nguyen, WH Norton… - Neuroscience & …, 2016 - Elsevier
Neurodevelopmental disorders (NDDs) are highly prevalent and severely debilitating brain
illnesses caused by aberrant brain growth and development. Resulting in cognitive, social …

Zebrafish as a robust preclinical platform for screening plant-derived drugs with anticonvulsant properties—a review

B Knap, D Nieoczym, U Kundap… - Frontiers in Molecular …, 2023 - frontiersin.org
Traditionally, selected plant sources have been explored for medicines to treat convulsions.
This continues today, especially in countries with low-income rates and poor medical …

Quercetin ameliorates lipopolysaccharide-induced neuroinflammation and oxidative stress in adult zebrafish

S Singh, K Sahu, L Kapil, C Singh, A Singh - Molecular Biology Reports, 2022 - Springer
Background Quercetin is a natural flavonoid that is known to have numerous
pharmacological activities such as antioxidative, anti-inflammatory, and neuroprotective …