Neutrophils in COVID-19

N Reusch, E De Domenico, L Bonaguro… - Frontiers in …, 2021 - frontiersin.org
Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that
neutrophils play an important role in the pathophysiology, particularly in those with severe …

Significance of NETs formation in COVID-19

K Janiuk, E Jabłońska, M Garley - Cells, 2021 - mdpi.com
Severe contagious respiratory disease—COVID-19—caused by the SARS-CoV-2
coronavirus, can lead to fatal respiratory failure associated with an excessive inflammatory …

High generation of reactive oxygen species from neutrophils in patients with severe COVID-19

T Veenith, H Martin, M Le Breuilly, T Whitehouse… - Scientific reports, 2022 - nature.com
Neutrophilia and an elevated neutrophil: lymphocyte ratio are both characteristic features of
severe COVID-19 infection. However, functional neutrophil responses have been poorly …

Neutrophils in COVID-19: recent insights and advances

J Li, K Zhang, ye Zhang, Z Gu, C Huang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can lead to acute …

Neutrophils and COVID-19: active participants and rational therapeutic targets

J Hazeldine, JM Lord - Frontiers in immunology, 2021 - frontiersin.org
Whilst the majority of individuals infected with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the causative pathogen of COVID-19, experience mild to …

Metoprolol in critically ill patients with COVID-19

A Clemente-Moragón, J Martínez-Milla, E Oliver… - Journal of the American …, 2021 - jacc.org
Background Severe coronavirus disease-2019 (COVID-19) can progress to an acute
respiratory distress syndrome (ARDS), which involves alveolar infiltration by activated …

Human endogenous retrovirus K in the respiratory tract is associated with COVID-19 physiopathology

JR Temerozo, N Fintelman-Rodrigues, MC Dos Santos… - Microbiome, 2022 - Springer
Background Critically ill 2019 coronavirus disease (COVID-19) patients under invasive
mechanical ventilation (IMV) are 10 to 40 times more likely to die than the general …

Anti-inflammatory and antimicrobial volatile oils: Fennel and cumin inhibit neutrophilic inflammation via regulating calcium and MAPKs

M Korinek, H Handoussa, YH Tsai, YY Chen… - Frontiers in …, 2021 - frontiersin.org
Neutrophilic inflammatory diseases, such as chronic obstructive pulmonary disease (COPD),
acute respiratory distress syndrome (ARDS), or psoriasis, exert a huge burden on the global …

Cell deaths: Involvement in the pathogenesis and intervention therapy of COVID-19

X Li, Z Zhang, Z Wang… - Signal transduction and …, 2022 - nature.com
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has dramatically influenced …

Severe COVID-19 shares a common neutrophil activation signature with other acute inflammatory states

LF Schimke, AHC Marques, GC Baiocchi… - Cells, 2022 - mdpi.com
Severe COVID-19 patients present a clinical and laboratory overlap with other
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …